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NAD-Dependent Deacetylase Sirtuin-2

Known as: Silent Information Regulator 2, EC 3.5.1.-, SIR2-Like Protein 2 
NAD-dependent deacetylase sirtuin-2 (389 aa, ~43 kDa) is encoded by the human SIRT2 gene. This protein plays a role in the deacetylation of tubulin.
National Institutes of Health

Papers overview

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Review
2013
Review
2013
  • Weiping Zheng
  • 2013
  • Corpus ID: 33728924
2011
2011
Resveratrol prolongs lifespan and prevent cancer formation; however, the mechanisms are not understood. Here we evaluated the… 
2008
2008
Sirtuins are conserved proteins implicated in myriad key processes including gene control, aging, cell survival, metabolism, and… 
2007
2007
Alcohol dehydrogenase 1 (Adh1)p catalyses the conversion of acetaldehyde to ethanol, regenerating NAD+. In Saccharomyces… 
Highly Cited
2006
Highly Cited
2006
Sirtuin 6 (SIRT6) is a member of the sirtuin deacetylases (sirtuins), which are derivatives of the yeast Silent information… 
2006
2006
Silent information regulator 2 (Sir2) is an NAD(+)-dependent histone deacetylase that establishes repressive chromatin status and…