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NAD(P)H dehydrogenase (quinone) 1, human
Known as:
EC 1.6.5.2
, Diaphorase-4
, NQO1
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NAD(P)H dehydrogenase [quinone] 1 (274 aa, ~31 kDa) is encoded by the human NQO1 gene. This protein is involved in hydroquinone synthesis.
National Institutes of Health
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Related topics
Related topics
14 relations
CRYZ gene
Enzyme Gene
FMN reductase
Hypoxia Pathway
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Broader (1)
NAD(P)H Dehydrogenase (Quinone)
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
Development of β-Lapachone Prodrugs for Therapy Against Human Cancer Cells with Elevated NAD(P)H:Quinone Oxidoreductase 1 Levels
Kathryn E. Reinicke
,
E. Bey
,
+10 authors
D. Boothman
Clinical Cancer Research
2005
Corpus ID: 21269590
β-Lapachone, an o-naphthoquinone, induces a novel caspase- and p53-independent apoptotic pathway dependent on NAD(P)H:quinone…
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Highly Cited
2003
Highly Cited
2003
An association between NQO1 genetic polymorphism and risk of bladder cancer.
Seun-Ja Park
,
Hua Zhao
,
M. Spitz
,
H. Grossman
,
Xifeng Wu
Mutation research
2003
Corpus ID: 29116066
Highly Cited
2003
Highly Cited
2003
Differential responses from seven mammalian cell lines to the treatments of detoxifying enzyme inducers.
Zhi-Qiang Jiang
,
Chi Chen
,
Bo Yang
,
V. Hebbar
,
A. Kong
Life Science
2003
Corpus ID: 34035256
Highly Cited
2001
Highly Cited
2001
NAD(P)H:quinone oxidoreductase 1 deficiency and increased susceptibility to 7,12-dimethylbenz[a]-anthracene-induced carcinogenesis in mouse skin.
D. J. Long
,
R. Waikel
,
Xiao-Jing Wang
,
Dennis R. Roop
,
Anil K. Jaiswal
Journal of the National Cancer Institute
2001
Corpus ID: 24999916
BACKGROUND The phase II enzyme NAD(P)H :quinone oxidoreductase 1 (NQO1) catalyzes quinone detoxification, protecting cells from…
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Review
1997
Review
1997
Investigations of bifidobacterial ecology and oligosaccharide metabolism in a three-stage compound continuous culture system.
A. McBain
,
G. Macfarlane
Scandinavian Journal of Gastroenterology…
1997
Corpus ID: 54487601
BACKGROUND Several different types of in vitro fermentation systems are currently employed to investigate pro- and prebiotic…
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Highly Cited
1994
Highly Cited
1994
F420H2: quinone oxidoreductase from Archaeoglobus fulgidus. Characterization of a membrane-bound multisubunit complex containing FAD and iron-sulfur clusters.
J. Kunow
,
D. Linder
,
K. Stetter
,
R. Thauer
European Journal of Biochemistry
1994
Corpus ID: 20664110
Archaeoglobus fulgidus, a hyperthermophilic sulfate-reducing archaeon, was found to contain a membrane-bound F420H2: quinone…
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Highly Cited
1992
Highly Cited
1992
Proton and electron transfer in the acceptor quinone complex of Rhodobacter sphaeroides reaction centers: characterization of site-directed mutants of the two ionizable residues, GluL212 and AspL213…
E. Takahashi
,
C. Wraight
Biochemistry
1992
Corpus ID: 6136317
Proton and electron transfer events in reaction centers (RCs) from Rhodobacter sphaeroides were investigated by site-directed…
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Highly Cited
1987
Highly Cited
1987
Zeta-crystallin, a novel lens protein from the guinea pig.
Q. Huang
,
P. Russell
,
S. H. Stone
,
J. Zigler
Current Eye Research
1987
Corpus ID: 44908977
Lens proteins from the guinea pig (Cavia porcellus) were found to be similar to those of other mammals with the exception of the…
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Highly Cited
1984
Highly Cited
1984
Na+ is translocated at NADH:quinone oxidoreductase segment in the respiratory chain of Vibrio alginolyticus.
H. Tokuda
,
T. Unemoto
Journal of Biological Chemistry
1984
Corpus ID: 30220425
Highly Cited
1975
Highly Cited
1975
Purification and properties of cellobiose: quinone oxidoreductase from Sporotrichum pulverulentum.
U. Westermark
,
K. Eriksson
Acta chemica Scandinavica. Series B: Organic…
1975
Corpus ID: 31827400
Cellobiose: quinone oxidoreductase was purified by ammonium sulfate precipitation, SP-Sephadex C-50 chromatography, and…
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