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NAD(P)H dehydrogenase (quinone) 1, human

Known as: EC 1.6.5.2, Diaphorase-4, NQO1 
NAD(P)H dehydrogenase [quinone] 1 (274 aa, ~31 kDa) is encoded by the human NQO1 gene. This protein is involved in hydroquinone synthesis.
National Institutes of Health

Related topics

Related topics

14 relations
CRYZ geneEnzyme GeneFMN reductaseHypoxia Pathway

Broader (1)

NAD(P)H Dehydrogenase (Quinone)

Papers overview

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Highly Cited
2005
Highly Cited
2005
Development of β-Lapachone Prodrugs for Therapy Against Human Cancer Cells with Elevated NAD(P)H:Quinone Oxidoreductase 1 Levels
β-Lapachone, an o-naphthoquinone, induces a novel caspase- and p53-independent apoptotic pathway dependent on NAD(P)H:quinone… 
Highly Cited
2003
Highly Cited
2003
An association between NQO1 genetic polymorphism and risk of bladder cancer.
Highly Cited
2003
Highly Cited
2003
Differential responses from seven mammalian cell lines to the treatments of detoxifying enzyme inducers.
Highly Cited
2001
Highly Cited
2001
NAD(P)H:quinone oxidoreductase 1 deficiency and increased susceptibility to 7,12-dimethylbenz[a]-anthracene-induced carcinogenesis in mouse skin.
BACKGROUND The phase II enzyme NAD(P)H :quinone oxidoreductase 1 (NQO1) catalyzes quinone detoxification, protecting cells from… 
Review
1997
Review
1997
Investigations of bifidobacterial ecology and oligosaccharide metabolism in a three-stage compound continuous culture system.
BACKGROUND Several different types of in vitro fermentation systems are currently employed to investigate pro- and prebiotic… 
Highly Cited
1994
Highly Cited
1994
F420H2: quinone oxidoreductase from Archaeoglobus fulgidus. Characterization of a membrane-bound multisubunit complex containing FAD and iron-sulfur clusters.
Archaeoglobus fulgidus, a hyperthermophilic sulfate-reducing archaeon, was found to contain a membrane-bound F420H2: quinone… 
Highly Cited
1992
Highly Cited
1992
Proton and electron transfer in the acceptor quinone complex of Rhodobacter sphaeroides reaction centers: characterization of site-directed mutants of the two ionizable residues, GluL212 and AspL213…
Proton and electron transfer events in reaction centers (RCs) from Rhodobacter sphaeroides were investigated by site-directed… 
Highly Cited
1987
Highly Cited
1987
Zeta-crystallin, a novel lens protein from the guinea pig.
Lens proteins from the guinea pig (Cavia porcellus) were found to be similar to those of other mammals with the exception of the… 
Highly Cited
1984
Highly Cited
1984
Na+ is translocated at NADH:quinone oxidoreductase segment in the respiratory chain of Vibrio alginolyticus.
Highly Cited
1975
Highly Cited
1975
Purification and properties of cellobiose: quinone oxidoreductase from Sporotrichum pulverulentum.
Cellobiose: quinone oxidoreductase was purified by ammonium sulfate precipitation, SP-Sephadex C-50 chromatography, and… 
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