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Hypoxia Pathway

Known as: Hypoxia and p53 in the Cardiovascular system 
Hypoxic stress, like DNA damage, induces p53 protein accumulation and p53-dependent apoptosis in oncogenically transformed cells. Unlike DNA damage… 
National Institutes of Health

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36 relations
ABCB1 protein, humanABCB1 wt AlleleAKT1 wt AlleleATM protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2016
Review
2016
Heritable Cancer Syndromes Related to the Hypoxia Pathway
Families of tumor-suppressor genes, such as those involved in homologous recombination or mismatch repair, contain individual… 
2015
2015
The effects of nonyl phenoxypolyethoxyl ethanol on cell damage pathway gene expression in SK-NSH cells
Background/Aims: Most pesticide formulations contain both chief and additive ingredients. But, the additives may not have been… 
2014
2014
Examining the Polymorphisms in the Hypoxia Pathway Genes in Relation to Outcome in Colorectal Cancer
Introduction Colorectal cancer is a common malignancy. Identification of genetic prognostic markers may help prognostic… 
2014
2014
Increased expression of the hypoxia‐related genes in peripheral blood leukocytes of human subjects with acute ischemic stroke
The present study was carried out to determine whether the peripheral blood leukocytes in patients with acute ischemic stroke… 
2013
2013
The Mechanisms of Chansu in Inducing Efficient Apoptosis in Colon Cancer Cells
Chansu is one of the most widely used traditional Chinese medicines in China, Japan, and other Southeast Asian countries… 
2012
2012
Gene expression profiles associated with anaemia and ITPA genotypes in patients with chronic hepatitis C (CH‐C)
Summary.  Anaemia is a common side effect of ribavirin (RBV) which is used for the treatment of hepatitis C. Inosine… 
2012
2012
Use of nano-immuno assay to generate rapid, quantitative nanoscale proteomic profiling of the hypoxia pathway in renal cell carcinoma clinical specimens.
10513 Background: Novel agents that inhibit kinases in the hypoxia pathway [VEGF, PDGF] can achieve response rates of 30-57% in… 
2010
2010
A system-level investigation into the cellular toxic response mechanism mediated by AhR signal transduction pathway
MOTIVATION Viewing a cellular system as a collection of interacting parts can lead to new insights into the complex cellular… 
Review
2009
Review
2009
Hypoxia response: a model toxicity pathway for high-throughput screening.
The identification of toxicity pathways associated with known adverse health effects combined with engineered cellular assays… 
Review
2008
Review
2008
Erythropoietin and microvascular diabetic complications.
When recombinant human erythropoietin (EPO) became available for clinical use, the hormone was considered as a specific… 
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