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N(7)-hydroxyethylguanine
Known as:
7-(2-hydroxyethyl)guanine
, N7-(2-hydroxyethyl)guanine
National Institutes of Health
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Related topics
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2 relations
Broader (1)
Guanine
analogs & derivatives
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Ethylene oxide and propylene oxide derived N7-alkylguanine adducts are bypassed accurately in vivo.
G. Philippin
,
J. Cadet
,
D. Gasparutto
,
G. Mazón
,
R. Fuchs
DNA Repair
2014
Corpus ID: 9091875
Review
2011
Review
2011
The application of mass spectrometry in molecular dosimetry: ethylene oxide as an example.
Kuen-Yuh Wu
,
S. Chiang
,
W. Shih
,
C. Huang
,
Ming-feng Chen
,
J. Swenberg
Mass spectrometry reviews (Print)
2011
Corpus ID: 24958226
Mass spectrometry plays an increasingly important role in the search for and quantification of novel chemically specific…
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2009
2009
DNA alkylation products formed by 1-(2-chloroethyl)-1-nitrosourea as molecular dosimeters of therapeutic response
W. Bodell
Journal of Neuro-Oncology
2009
Corpus ID: 7817679
This study has investigated if individual DNA adducts formed in human glioma cells treated with 3H-1-(2-chloroethyl)-1…
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2005
2005
The carcinogenic significance of reactive intermediates derived from 3-acetoxy- and 5-acetoxy-2-hydroxy-N-nitrosomorpholine.
R. Loeppky
,
Sunil Sukhtankar
,
F. Gu
,
Misun Park
Chemical Research in Toxicology
2005
Corpus ID: 43805542
N-Nitroso-2-hydroxymorpholine (NHMOR), a relatively reactive metabolite of two potent carcinogens, N-nitrosodiethanolamine (NDELA…
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1999
1999
Comparison of (32)P-postlabeling and high-resolution GC/MS in quantifying N7-(2-Hydroxyethyl)guanine adducts.
I. Eide
,
C. Zhao
,
R. Kumar
,
K. Hemminki
,
K. Wu
,
J. Swenberg
Chemical Research in Toxicology
1999
Corpus ID: 19822929
This study compares (32)P-postlabeling and high-resolution gas chromatography/mass spectrometry (GC/MS) in the quantification of…
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1994
1994
Comparison of various immunochemical assays for the detection of ethylene oxide-DNA adducts with monoclonal antibodies against imidazole ring-opened N7-(2-hydroxyethyl)guanosine: application in a…
J. V. van Delft
,
M. V. van Winden
,
A. Luiten-Schuite
,
L. R. Ribeiro
,
R. Baan
Carcinogenesis
1994
Corpus ID: 28323723
Monoclonal antibodies have been developed for the analysis of the predominant lesion in DNA induced by ethylene oxide (EtOx…
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1992
1992
Activation of a beta-hydroxyalkylnitrosamine to alkylating agents: evidence for the involvement of a sulfotransferase.
M. B. Kroeger-Koepke
,
S. Koepke
,
L. Hernandez
,
C. Michejda
Cancer Research
1992
Corpus ID: 34448951
N-Nitrosomethyl(2-hydroxyethyl)amine (NMHEA), when administered by gavage, is a strong liver carcinogen in F344 female rats, but…
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1991
1991
Release of 7-alkylguanines from N-(2-chloroethyl)-N'-cyclohexyl-N-nitrosourea-modified DNA by 3-methyladenine DNA glycosylase II.
Y. Habraken
,
C. A. Carter
,
M. Kirk
,
D. Ludlum
Cancer Research
1991
Corpus ID: 14500936
Purified bacterial 3-methyladenine DNA glycosylase II releases four 7-alkylguanines from [3H]N-(2-chloroethyl)-N'-cyclohexyl-N…
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1990
1990
Preparation of electrophoric derivatives of N7-(2-hydroxyethyl)guanine, an ethylene oxide DNA adduct.
K. Allam
,
M. Saha
,
R. Giese
Journal of Chromatography A
1990
Corpus ID: 19386869
1986
1986
Modification of DNA and metabolism of ethyl carbamate in vivo: formation of 7-(2-oxoethyl)guanine and its sensitive determination by reductive tritiation using 3H-sodium borohydride.
E. Scherer
,
H. Winterwerp
,
P. Emmelot
IARC scientific publications
1986
Corpus ID: 24640108
The modification of liver DNA of mice and rats by ethyl carbamate and its putative proximate metabolite, vinyl carbamate, has…
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