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N(7)-hydroxyethylguanine

Known as: 7-(2-hydroxyethyl)guanine, N7-(2-hydroxyethyl)guanine 
 
National Institutes of Health

Papers overview

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2009
2009
Ethylene oxide (EO) is widely used in the chemical industry and is also formed in humans through the metabolic oxidation of… Expand
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2005
2005
Ethylene oxide (EO) is an important industrial chemical that is classified as a known human carcinogen (IARC, Group 1). It is… Expand
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2005
2005
  • C. Kao, R. Giese
  • Chemical research in toxicology
  • 2005
  • Corpus ID: 28434019
An improved method is presented, based on gas chromatography-electron capture mass spectrometry (GC-EC-MS), for measuring N7-(2… Expand
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Review
2000
Review
2000
  • H. Bolt
  • Critical reviews in toxicology
  • 2000
  • Corpus ID: 21154564
ABSTRACT Long-term inhalation studies in rodents have presented unequivocal evidence of experimental carcinogenicity of ethylene… Expand
2000
2000
Ethylene oxide (EO) is mutagenic in various in vitro and in vivo test systems and carcinogenic in rodents. EO forms different… Expand
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1999
1999
A gas chromatography/electron capture/negative chemical ionization high-resolution mass spectrometry (GC/EC/NCI-HRMS) method was… Expand
1997
1997
Abstract A newly developed high-performance liquid chromatography (HPLC) method involves derivatization with phenylglyoxal and… Expand
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1993
1993
We have synthesized 1-[N3-(2'-deoxycytidyl)]-2-[N1-(2'-deoxyguanosinyl)]ethane and confirmed its structure by ultraviolet and… Expand
Highly Cited
1992
Highly Cited
1992
The formation of 7-(2-hydroxyethyl)guanine (7-HEG) in DNA of target and nontarget tissues was investigated in male B6C3F1 mice… Expand
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1986
1986
The modification of liver DNA of mice and rats by ethyl carbamate and its putative proximate metabolite, vinyl carbamate, has… Expand