Skip to search formSkip to main contentSkip to account menu

N(7)-hydroxyethylguanine

Known as: 7-(2-hydroxyethyl)guanine, N7-(2-hydroxyethyl)guanine 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Guanine
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Ethylene oxide and propylene oxide derived N7-alkylguanine adducts are bypassed accurately in vivo.
2009
2009
DNA alkylation products formed by 1-(2-chloroethyl)-1-nitrosourea as molecular dosimeters of therapeutic response
This study has investigated if individual DNA adducts formed in human glioma cells treated with 3H-1-(2-chloroethyl)-1… 
2008
2008
Rapid and sensitive on-line liquid chromatographic/tandem mass spectrometric determination of an ethylene oxide-DNA adduct, N7-(2-hydroxyethyl)guanine, in urine of nonsmokers.
Ethylene oxide (EtO) is classified as a known human carcinogen. The formation of EtO-DNA adducts is considered as an important… 
2007
2007
DNA adducts in granulocytes of hospital workers exposed to ethylene oxide.
BACKGROUND Ethylene oxide (EtO), an important industrial chemical intermediate and sterilant, is classified as a human carcinogen… 
2002
2002
Differential induction of N(2),3-ethenoguanine in rat brain and liver after exposure to vinyl chloride.
Although vinyl chloride (VC) clearly induces hepatic angiosarcoma in humans and rodents, a causal association with brain tumors… 
1999
1999
Comparison of (32)P-postlabeling and high-resolution GC/MS in quantifying N7-(2-Hydroxyethyl)guanine adducts.
This study compares (32)P-postlabeling and high-resolution gas chromatography/mass spectrometry (GC/MS) in the quantification of… 
1997
1997
High-performance liquid chromatography/electrospray mass spectrometry for the analysis of modified bases in DNA: 7-(2-hydroxyethyl)guanine, the major ethylene oxide-DNA adduct.
A method was developed for the analysis of 7-(2-hydroxyethyl)guanine (7HEG), the major DNA adduct formed after exposure to… 
1992
1992
Activation of a beta-hydroxyalkylnitrosamine to alkylating agents: evidence for the involvement of a sulfotransferase.
N-Nitrosomethyl(2-hydroxyethyl)amine (NMHEA), when administered by gavage, is a strong liver carcinogen in F344 female rats, but… 
1990
1990
Preparation of electrophoric derivatives of N7-(2-hydroxyethyl)guanine, an ethylene oxide DNA adduct.
1986
1986
Modification of DNA and metabolism of ethyl carbamate in vivo: formation of 7-(2-oxoethyl)guanine and its sensitive determination by reductive tritiation using 3H-sodium borohydride.
The modification of liver DNA of mice and rats by ethyl carbamate and its putative proximate metabolite, vinyl carbamate, has… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)