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Mycophenolic Acid

Known as: Mycophenolsäure, Micofenolico acido, 4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-, (E)- 
An antineoplastic antibiotic derived from various Penicillium fungal species. Mycophenolic acid is an active metabolite of the prodrug mycophenolate… 
National Institutes of Health

Related topics

Related topics

36 relations

Narrower (14)

1,3-dipalmitoyl-2-mycophenoloyl glycerolC2-mycophenolic adenine dinucleotideC4-mycophenolic adenine dinucleotideCellcept

Broader (5)

Antibiotics, AntineoplasticAntibiotics, AntitubercularBenzofuransEnzyme Inhibitors
Decreased Immunologic Activity [PE]Drug AllergyGraft-vs-Host DiseaseIn Blood

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Everolimus Plus Reduced‐Exposure CsA versus Mycophenolic Acid Plus Standard‐Exposure CsA in Renal‐Transplant Recipients
Everolimus allows calcineurin‐inhibitor reduction without loss of efficacy and may improve renal‐transplant outcomes. In a 24… 
Review
2003
Review
2003
Mycophenolic Acid Pharmacodynamics and Pharmacokinetics Provide a Basis for Rational Monitoring Strategies
Mycophenolic acid (MPA), the active immunosuppressant form of the pro-drug mycophenolate mofetil (MMF), is a widely used… 
Highly Cited
2002
Highly Cited
2002
The pharmacokinetic-pharmacodynamic relationship for total and free mycophenolic Acid in pediatric renal transplant recipients: a report of the german study group on mycophenolate mofetil therapy.
It is currently being debated whether pharmacokinetic monitoring of mycophenolic acid (MPA), the active constituent of… 
Review
2001
Review
2001
Current Issues in Therapeutic Drug Monitoring of Mycophenolic Acid: Report of a Roundtable Discussion
This review is based on a roundtable discussion held under the auspices of F. Hoffman-LaRoche in Nice, France, in December 1999… 
Review
2000
Review
2000
Immunosuppressive drugs: the first 50 years and a glance forward.
Highly Cited
1998
Highly Cited
1998
The pharmacokinetic‐pharmacodynamic relationship for mycophenolate mofetil in renal transplantation
Review
1993
Review
1993
Immunosuppressive and other Effects of Mycophenolic Acid and an Ester Prodrug, Mycophenolate Mofetil
The advantages and limitations of currently used immunosuppressive drugs are well known. Each drug has specific side effects: for… 
Highly Cited
1991
Highly Cited
1991
Lymphocyte‐Selective Cytostatic and Immunosuppressive Effects of Mycophenolic Acid in Vitro: Role of Deoxyguanosine Nucleotide Depletion
Mycophenolic acid (MPA), an inhibitor of inosine monophosphate dehydrogenase, in nanomolar concentrations blocks proliferative… 
Highly Cited
1991
Highly Cited
1991
Myxoma virus expresses a secreted protein with homology to the tumor necrosis factor receptor gene family that contributes to viral virulence.
Highly Cited
1981
Highly Cited
1981
Selection for animal cells that express the Escherichia coli gene coding for xanthine-guanine phosphoribosyltransferase.
Cultured monkey (TC7) and mouse (3T6) cells synthesize an Excherichia coli enzyme, xanthine-guanine phosphoribosyltransferase… 
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