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Mycophenolic Acid

Known as: Mycophenolsäure, Micofenolico acido, 4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-, (E)- 
An antineoplastic antibiotic derived from various Penicillium fungal species. Mycophenolic acid is an active metabolite of the prodrug mycophenolate… 
National Institutes of Health

Related topics

Related topics

36 relations

Narrower (14)

1,3-dipalmitoyl-2-mycophenoloyl glycerolC2-mycophenolic adenine dinucleotideC4-mycophenolic adenine dinucleotideCellcept

Broader (5)

Antibiotics, AntineoplasticAntibiotics, AntitubercularBenzofuransEnzyme Inhibitors
Decreased Immunologic Activity [PE]Drug AllergyGraft-vs-Host DiseaseIn Blood

Papers overview

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2012
2012
Mycophenolic acid-related anemia and leucopenia in renal transplant recipients are related to genetic polymorphisms in CYP2C8.
W ith great interest we read the article by Jacobson et al. (1) who observed that single-nucleotide polymorphisms (SNPs) in IL12A… 
2011
2011
Mycophenolic Acid Pharmacokinetics During Maintenance Immunosuppression in African American and Caucasian Renal Transplant Recipients
Renal transplant recipients exhibit variability in mycophenolic acid (MPA) and MPA glucuronide (MPAG) pharmacokinetics, which are… 
2010
2010
Producers of mycophenolic acid in ensiled and grain feeds
Using the reaction of activated N-hydrooxisuccinimide ester of mycophenolic acid, a series of immunoreactive conjugated antigens… 
Review
2008
Review
2008
Drug-Drug Interactions With Immunosuppressive Agents: Review of the In Vitro Functional Assays and Role of Cytochrome P450 Enzymes
Frequency of drug-drug interaction is high in most solid organ transplant recipients because of polypharmacy. These interactions… 
2007
2007
Investigation on pharmacokinetics of mycophenolic acid in Chinese adult renal transplant patients.
We read with interest the recent paper by Zicheng et al. [1] on pharmacokinetics of mycophenolic acid (MPA) in Chinese renal… 
1999
1999
Pharmacokinetics of mycophenolic acid (MPA) and free MPA in paediatric renal transplant recipients--a multicentre study. The German Study Group on Mycophenolate Mofetil (MMF) Therapy.
tion finished at day 9. This short observation time was chosen in order to improve the rate of reply of the centres to whom we… 
1986
1986
Preparation of dextran T70-methotrexate conjugate and dextran T70-mycophenolic acid conjugate, and in vitro effect of dextran T70-methotrexate on dihydrofolate reductase.
Alkylenediamine-dextran T70(T70-Cn) might be useful as a polymer support for anti-tumor polymeric drugs, and its preparation was… 
1985
1985
Rapid assay for detection of Escherichia coli xanthine-guanine phosphoribosyltransferase activity in transduced cells.
Cultured mammalian cells transduced with the Escherichia coli gene, Ecogpt, synthesize the bacterial enzyme xanthine-guanine… 
1981
1981
Mutagen-induced resistance to mycophenolic acid in hamster cells can be associated with increased inosine 5'-phosphate dehydrogenase activity.
Cell variants resistant to the cytotoxic effect of mycophenolic acid, an inhibitor of IMP dehydrogenase (IMP:NAD+ oxidoreductase… 
1973
1973
Properties of inosinic acid dehydrogenase from Bacillus subtilis. II. Kinetic properties.
Some of the kinetic properties of inosine 5′-phosphate (IMP) dehydrogenase purified from Bacillus subtilis have been described. K…