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With the increasing use of mycophenolic acid (MPA) in solid organ transplantation, the need for more accurate drug dosing has… Expand Large between- and within-patient variability has been observed in the pharmacokinetics of mycophenolic acid (MPA). However… Expand In mycophenolate mofetil (MMF)‐treated organ transplant recipients, lower mycophenolic acid (MPA) plasma concentrations have been… Expand Mycophenolic acid (MPA), the active metabolite of the immunosuppressant mycophenolate mofetil is primarily metabolized by… Expand SummaryThe pharmacokinetics of the immunosuppressant mycophenolate mofetil have been investigated in healthy volunteers and… Expand The structure of inosine-5'-monophosphate dehydrogenase (IMPDH) in complex with IMP and mycophenolic acid (MPA) has been… Expand Mycophenolate mofetil, the prodrug form of the immunosuppressive agent mycophenolic acid (MPA), is currently in clinical trials… Expand The advantages and limitations of currently used immunosuppressive drugs are well known. Each drug has specific side effects: for… Expand Mycophenolic acid (MPA), an inhibitor of inosine monophosphate dehydrogenase, in nanomolar concentrations blocks proliferative… Expand 1. Mycophenolic acid, an antibiotic of some antiquity that more recently has been found to have marked activity against a range… Expand