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Mycophenolic Acid

Known as: Mycophenolsäure, Micofenolico acido, 4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-, (E)- 
An antineoplastic antibiotic derived from various Penicillium fungal species. Mycophenolic acid is an active metabolite of the prodrug mycophenolate… Expand
National Institutes of Health

Papers overview

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Review
2010
Review
2010
With the increasing use of mycophenolic acid (MPA) in solid organ transplantation, the need for more accurate drug dosing has… Expand
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Highly Cited
2006
Highly Cited
2006
Large between- and within-patient variability has been observed in the pharmacokinetics of mycophenolic acid (MPA). However… Expand
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Highly Cited
2005
Highly Cited
2005
In mycophenolate mofetil (MMF)‐treated organ transplant recipients, lower mycophenolic acid (MPA) plasma concentrations have been… Expand
Highly Cited
2005
Highly Cited
2005
Mycophenolic acid (MPA), the active metabolite of the immunosuppressant mycophenolate mofetil is primarily metabolized by… Expand
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Review
1998
Review
1998
SummaryThe pharmacokinetics of the immunosuppressant mycophenolate mofetil have been investigated in healthy volunteers and… Expand
Highly Cited
1996
Highly Cited
1996
The structure of inosine-5'-monophosphate dehydrogenase (IMPDH) in complex with IMP and mycophenolic acid (MPA) has been… Expand
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Highly Cited
1995
Highly Cited
1995
Mycophenolate mofetil, the prodrug form of the immunosuppressive agent mycophenolic acid (MPA), is currently in clinical trials… Expand
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Review
1993
Review
1993
The advantages and limitations of currently used immunosuppressive drugs are well known. Each drug has specific side effects: for… Expand
Highly Cited
1991
Highly Cited
1991
Mycophenolic acid (MPA), an inhibitor of inosine monophosphate dehydrogenase, in nanomolar concentrations blocks proliferative… Expand
Highly Cited
1969
Highly Cited
1969
1. Mycophenolic acid, an antibiotic of some antiquity that more recently has been found to have marked activity against a range… Expand
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