Skip to search formSkip to main contentSkip to account menu

Multidrug Resistance-Associated Proteins

Known as: Multispecific Organic Anion Transporter, Multidrug Resistance-Associated Proteins [Chemical/Ingredient], Resistance-Associated Protein, Multidrug 
A sequence-related subfamily of ATP-BINDING CASSETTE TRANSPORTERS that actively transport organic substrates. Although considered organic anion… 
National Institutes of Health

Related topics

Related topics

27 relations
ABCC1 geneABCC1 wt AlleleIn BloodMulti-Drug Resistance

Narrower (14)

ABCC10 protein, humanABCC5 protein, humanABCC6 protein, humanAbcc4 protein, rat

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2002
Review
2002
Drug resistance caused by multidrug resistance-associated proteins.
Three types of drug efflux pumps, the multidrug resistance gene 1 (MDR1 or ABCB1)-encoded P glycoprotein, the multidrug… 
Highly Cited
2001
Highly Cited
2001
Identification of the Apical Membrane-targeting Signal of the Multidrug Resistance-associated Protein 2 (MRP2/cMOAT)*
The human canalicular multispecific organic anion transporter (cMOAT), known as the multidrug resistance-associated protein 2… 
Highly Cited
2001
Highly Cited
2001
Expression of MRP1 and related transporters in human lung cells in culture.
Highly Cited
2001
Highly Cited
2001
Calcein assay for multidrug resistance reliably predicts therapy response and survival rate in acute myeloid leukaemia
In this study, we evaluated the suitability of the calcein assay as a routine clinical laboratory method for the identification… 
Highly Cited
2000
Highly Cited
2000
Discovery and characterization of OC144-093, a novel inhibitor of P-glycoprotein-mediated multidrug resistance.
OC144-093 is a novel substituted diarylimidazole (Mr 495) generated using the OntoBLOCK system, a solid-phase combinatorial… 
Review
1999
Review
1999
Resistance to cisplatin.
Resistance to cis-diamminedichloroplatinum(II) (cisplatin), a DNA damaging agent, is a major obstacle for its clinical… 
Highly Cited
1999
Highly Cited
1999
Direct interaction between a quinoline derivative, MS-209, and multidrug resistance protein (MRP) in human gastric cancer cells.
MS-209 is a novel quinoline derivative reversing P-glycoprotein-mediated multidrug resistance (MDR). We investigated the… 
Review
1998
Review
1998
Biochemical and clinical aspects of efflux pump related resistance to anti-cancer drugs.
This review paper will focus on the molecular biological, biochemical and biophysical aspects of the following three efflux pumps… 
Review
1996
Review
1996
Multidrug resistance-associated protein (MRP) in haematological malignancies.
The presence of multidrug resistant cells, either acquired or de novo, severely limits treatment outcome in haematological… 
Highly Cited
1994
Highly Cited
1994
Analysis of multidrug resistance-associated protein (MRP) messenger RNA in normal and malignant hematopoietic cells.
The multidrug resistance-associated protein (MRP) gene is a member of the ATP-binding cassette transporter gene superfamily and… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)