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Multidrug Resistance-Associated Proteins

Known as: Multispecific Organic Anion Transporter, Multidrug Resistance-Associated Proteins [Chemical/Ingredient], Resistance-Associated Protein, Multidrug 
A sequence-related subfamily of ATP-BINDING CASSETTE TRANSPORTERS that actively transport organic substrates. Although considered organic anion… Expand
National Institutes of Health

Papers overview

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Review
2016
Review
2016
Chemotherapy is one of the prevailing methods used to treat malignant tumours, but the outcome and prognosis of tumour patients… Expand
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Review
2016
Review
2016
Multidrug resistance (MDR) is a serious phenomenon employed by cancer cells which hampers the success of cancer pharmacotherapy… Expand
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Highly Cited
2002
Highly Cited
2002
Inhibitors of the breast cancer resistance protein (BCRP/ABCG2) multidrug transporter are of interest as chemosensitizers for… Expand
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Review
2000
Review
2000
The human multidrug resistance-associated protein (MRP) family currently has seven members. The ability of several of these… Expand
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Highly Cited
1999
Highly Cited
1999
The blood-brain barrier and a blood-cerebrospinal-fluid (CSF) barrier function together to isolate the brain from circulating… Expand
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Highly Cited
1999
Highly Cited
1999
Several members of the multidrug resistance protein (MRP) family are expressed in the liver. Adenosine triphosphate (ATP… Expand
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Highly Cited
1997
Highly Cited
1997
By screening databases of human expressed sequence tags, we have identified three new homologues of MRP1, the gene encoding the… Expand
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Highly Cited
1996
Highly Cited
1996
The human Dubin-Johnson syndrome and its animal model, the TR(-) rat, are characterized by a chronic conjugated… Expand
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Highly Cited
1995
Highly Cited
1995
Multidrug-resistant cancer cells frequently overexpress the 110-kD LRP protein (originally named Lung Resistance-related Protein… Expand
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Highly Cited
1994
Highly Cited
1994
Amplification of the gene encoding multidrug resistance-associated protein (MRP) and overexpression of its cognate mRNA have been… Expand
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