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Multidrug Resistance-Associated Proteins

Known as: Multispecific Organic Anion Transporter, Multidrug Resistance-Associated Proteins [Chemical/Ingredient], Resistance-Associated Protein, Multidrug 
A sequence-related subfamily of ATP-BINDING CASSETTE TRANSPORTERS that actively transport organic substrates. Although considered organic anion… 
National Institutes of Health

Papers overview

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Highly Cited
2002
Highly Cited
2002
Inhibitors of the breast cancer resistance protein (BCRP/ABCG2) multidrug transporter are of interest as chemosensitizers for… 
Review
2000
Review
2000
The human multidrug resistance-associated protein (MRP) family currently has seven members. The ability of several of these… 
Highly Cited
1999
Highly Cited
1999
The blood-brain barrier and a blood-cerebrospinal-fluid (CSF) barrier function together to isolate the brain from circulating… 
Highly Cited
1997
Highly Cited
1997
By screening databases of human expressed sequence tags, we have identified three new homologues of MRP1, the gene encoding the… 
Highly Cited
1997
Highly Cited
1997
The multidrug resistance-associated protein (MRP) mediates the cellular excretion of many drugs, glutathione S-conjugates (GS-X… 
Highly Cited
1996
Highly Cited
1996
The human Dubin-Johnson syndrome and its animal model, the TR− rat, are characterized by a chronic conjugated hyperbilirubinemia… 
Highly Cited
1995
Highly Cited
1995
Multidrug-resistant cancer cells frequently overexpress the 110-kD LRP protein (originally named Lung Resistance-related Protein… 
Highly Cited
1995
Highly Cited
1995
The multidrug resistant cell lines HL60/AR and GLC4/ADR show high overexpression of the gene encoding the multidrug resistance… 
Highly Cited
1994
Highly Cited
1994
The multidrug-resistance associated protein MRP is a 180- to 195-kDa membrane protein associated with resistance of human tumor… 
Highly Cited
1994
Highly Cited
1994
Amplification of the gene encoding multidrug resistance-associated protein (MRP) and overexpression of its cognate mRNA have been…