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Multidrug Resistance-Associated Proteins
Known as:
Multispecific Organic Anion Transporter
, Multidrug Resistance-Associated Proteins [Chemical/Ingredient]
, Resistance-Associated Protein, Multidrug
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A sequence-related subfamily of ATP-BINDING CASSETTE TRANSPORTERS that actively transport organic substrates. Although considered organic anion…
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National Institutes of Health
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Related topics
Related topics
27 relations
ABCC1 gene
ABCC1 wt Allele
In Blood
Multi-Drug Resistance
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Narrower (14)
ABCC10 protein, human
ABCC5 protein, human
ABCC6 protein, human
Abcc4 protein, rat
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2002
Review
2002
Drug resistance caused by multidrug resistance-associated proteins.
J. Wijnholds
Novartis Foundation symposium
2002
Corpus ID: 31237924
Three types of drug efflux pumps, the multidrug resistance gene 1 (MDR1 or ABCB1)-encoded P glycoprotein, the multidrug…
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Highly Cited
2001
Highly Cited
2001
Identification of the Apical Membrane-targeting Signal of the Multidrug Resistance-associated Protein 2 (MRP2/cMOAT)*
M. Harris
,
M. Kuwano
,
Malcolm Webb
,
P. Board
Journal of Biological Chemistry
2001
Corpus ID: 35485686
The human canalicular multispecific organic anion transporter (cMOAT), known as the multidrug resistance-associated protein 2…
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Highly Cited
2001
Highly Cited
2001
Expression of MRP1 and related transporters in human lung cells in culture.
Thomas Lehmann
,
Christoph Köhler
,
Enrico Weidauer
,
Christiane Taege
,
H. Foth
Toxicology
2001
Corpus ID: 1036957
Highly Cited
2001
Highly Cited
2001
Calcein assay for multidrug resistance reliably predicts therapy response and survival rate in acute myeloid leukaemia
É. Karászi
,
K. Jakab
,
+8 authors
J. Kappelmayer
British Journal of Haematology
2001
Corpus ID: 12257913
In this study, we evaluated the suitability of the calcein assay as a routine clinical laboratory method for the identification…
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Highly Cited
2000
Highly Cited
2000
Discovery and characterization of OC144-093, a novel inhibitor of P-glycoprotein-mediated multidrug resistance.
M. J. Newman
,
Jennifer C. Rodarte
,
+8 authors
L. Mayer
Cancer Research
2000
Corpus ID: 64973
OC144-093 is a novel substituted diarylimidazole (Mr 495) generated using the OntoBLOCK system, a solid-phase combinatorial…
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Review
1999
Review
1999
Resistance to cisplatin.
S. Akiyama
,
Zhe-Sheng Chen
,
T. Sumizawa
,
T. Furukawa
Anti-Cancer Drug Design
1999
Corpus ID: 31139107
Resistance to cis-diamminedichloroplatinum(II) (cisplatin), a DNA damaging agent, is a major obstacle for its clinical…
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Highly Cited
1999
Highly Cited
1999
Direct interaction between a quinoline derivative, MS-209, and multidrug resistance protein (MRP) in human gastric cancer cells.
Takashi Nakamura
,
Mikio Oka
,
+9 authors
Shigeru Kohno
Biochemical and Biophysical Research…
1999
Corpus ID: 9164132
MS-209 is a novel quinoline derivative reversing P-glycoprotein-mediated multidrug resistance (MDR). We investigated the…
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Review
1998
Review
1998
Biochemical and clinical aspects of efflux pump related resistance to anti-cancer drugs.
Adorjan Aszalos
,
Ross Dd
Anticancer Research
1998
Corpus ID: 7591042
This review paper will focus on the molecular biological, biochemical and biophysical aspects of the following three efflux pumps…
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Review
1996
Review
1996
Multidrug resistance-associated protein (MRP) in haematological malignancies.
K. Nooter
,
H. Burger
,
G. Stoter
Leukemia and Lymphoma
1996
Corpus ID: 38722142
The presence of multidrug resistant cells, either acquired or de novo, severely limits treatment outcome in haematological…
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Highly Cited
1994
Highly Cited
1994
Analysis of multidrug resistance-associated protein (MRP) messenger RNA in normal and malignant hematopoietic cells.
M. Abbaszadegan
,
B. Futscher
,
Walter T. Klimecki
,
Alan F. List
,
William S. Dalton
Cancer Research
1994
Corpus ID: 35884479
The multidrug resistance-associated protein (MRP) gene is a member of the ATP-binding cassette transporter gene superfamily and…
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