Multidrug Resistance-Associated Proteins

Known as: Multispecific Organic Anion Transporter, Multidrug Resistance-Associated Proteins [Chemical/Ingredient], Resistance-Associated Protein, Multidrug 
A sequence-related subfamily of ATP-BINDING CASSETTE TRANSPORTERS that actively transport organic substrates. Although considered organic anion… (More)

Topic mentions per year

Topic mentions per year

1987-2017
05010015019872017

Papers overview

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Highly Cited
2007
Highly Cited
2007
UNLABELLED Multidrug resistance-associated proteins (Mrps) are adenosine triphosphate-dependent transporters that efflux… (More)
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Highly Cited
2004
Highly Cited
2004
Anthocyanin biosynthesis is one of the most thoroughly studied enzymatic pathways in biology, but little is known about the… (More)
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Highly Cited
2002
Highly Cited
2002
The multidrug resistance-associated protein 2 (MRP2, ABCC2), mediates the efflux of several conjugated compounds across the… (More)
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Highly Cited
1999
Highly Cited
1999
The blood-brain barrier and a blood-cerebrospinal-fluid (CSF) barrier function together to isolate the brain from circulating… (More)
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Highly Cited
1999
Highly Cited
1999
Therapeutic resistance is a major obstacle in the treatment of acute myeloid leukemia (AML). Such resistance has been associated… (More)
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Highly Cited
1999
Highly Cited
1999
BACKGROUND Human cancer cell lines grown in the presence of the cytotoxic agent mitoxantrone frequently develop resistance… (More)
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Highly Cited
1997
Highly Cited
1997
By screening databases of human expressed sequence tags, we have identified three new homologues of MRP1, the gene encoding the… (More)
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Highly Cited
1997
Highly Cited
1997
The multidrug resistance-associated protein (MRP) mediates the cellular excretion of many drugs, glutathione S-conjugates (GS-X… (More)
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Highly Cited
1994
Highly Cited
1994
The multidrug-resistance associated protein MRP is a 180- to 195-kDa membrane protein associated with resistance of human tumor… (More)
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Highly Cited
1994
Highly Cited
1994
Amplification of the gene encoding multidrug resistance-associated protein (MRP) and overexpression of its cognate mRNA have been… (More)
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