ABCC5 protein, human

Known as: ATP-binding cassette, sub-family C (CFTR-MRP), member 5 protein, human, MRP5 transport protein, human, pABC11 protein, human 
Multidrug resistance-associated protein 5 (1437 aa, ~161 kDa) is encoded by the human ABCC5 gene. This protein plays a role in the export of cyclic… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1999-2018
051019992018

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2013
2013
BACKGROUND Although a large set of full-length transcripts was recently assembled in catfish, annotation of large gene families… (More)
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2012
2012
UNLABELLED Adenosine triphosphate (ATP)-binding cassette (ABC) transporters are drug efflux pumps responsible for the multidrug… (More)
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Highly Cited
2011
Highly Cited
2011
PURPOSE Tumor-initiating cells are resistant to chemotherapy, but how microRNAs play a role in regulating drug resistance of… (More)
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2007
2007
cGMP secretion from cells can be mediated by ATP-binding cassette (ABC) transporters ABCC4, ABCC5, and ABCC11. Indirect evidence… (More)
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2006
2006
We examined the expression levels of the multidrug resistance protein 5 (ABCC5) gene in non-small cell lung cancer (NSCLC) cell… (More)
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Highly Cited
2005
Highly Cited
2005
5'-Fluorouracil (5-FU), used in the treatment of colon and breast cancers, is converted intracellularly to 5'-fluoro-2… (More)
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Highly Cited
2005
Highly Cited
2005
Delivery of therapeutic agents to the brain and its neoplasms depends on the presence of membrane transport proteins in the blood… (More)
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2004
2004
Although 40–50% of non-small cell lung cancer (NSCLC) tumors respond to cisplatin chemotherapy, there currently is no way to… (More)
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Highly Cited
2000
Highly Cited
2000
Cellular export of cyclic nucleotides has been observed in various tissues and may represent an elimination pathway for these… (More)
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Highly Cited
1999
Highly Cited
1999
Several members of the ABC family of proteins have been implicated in multidrug resistance associated with cancer therapies. A… (More)
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