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ABCC5 protein, human

Known as: ATP-binding cassette, sub-family C (CFTR-MRP), member 5 protein, human, MRP5 transport protein, human, pABC11 protein, human 
Multidrug resistance-associated protein 5 (1437 aa, ~161 kDa) is encoded by the human ABCC5 gene. This protein plays a role in the export of cyclic… Expand
National Institutes of Health

Papers overview

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2017
2017
Paclitaxel is clinically used as a first-line chemotherapeutic regimen for several cancer types, including head and neck cancers… Expand
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Highly Cited
2011
Highly Cited
2011
Purpose: Tumor-initiating cells are resistant to chemotherapy, but how microRNAs play a role in regulating drug resistance of… Expand
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Highly Cited
2008
Highly Cited
2008
OBJECTIVE Tumor markers with increased sensitivity and specificity for endometrial cancer are needed to help monitor response to… Expand
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Review
2008
Review
2008
Assays measuring SMRP (mesothelin) and HE4 (a secreted protease) in serum and other body fluids (including urine for SMRP) are… Expand
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Highly Cited
2007
Highly Cited
2007
Purpose: High levels of serum-soluble mesothelin family proteins (SMRP) have been found to be associated with malignant… Expand
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Diagnosis of malignant pleural mesothelioma is a challenging issue. Potential markers in mesothelioma diagnosis… Expand
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Highly Cited
2005
Highly Cited
2005
5′-Fluorouracil (5-FU), used in the treatment of colon and breast cancers, is converted intracellularly to 5′-fluoro-2… Expand
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Review
2005
Review
2005
Like other members of the multidrug resistance protein (MRP)/ABCC subfamily of ATP-binding cassette transporters, MRP4 (ABCC4… Expand
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Highly Cited
2005
Highly Cited
2005
Delivery of therapeutic agents to the brain and its neoplasms depends on the presence of membrane transport proteins in the blood… Expand
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Highly Cited
2004
Highly Cited
2004
BackgroundAlthough 40–50% of non-small cell lung cancer (NSCLC) tumors respond to cisplatin chemotherapy, there currently is no… Expand
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