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Multi-Drug Resistance

Known as: Multidrug Resistance, Resistance, Multiple Drug, Multiple drug resistance 
Simultaneous resistance to a spectrum of unrelated drugs following exposure to a single agent. Mechanisms involve expression of multidrug efflux… Expand
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Preventing and controlling resistance requires the engagement of many different sectors of society. However, the physician's role… Expand
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Highly Cited
2012
Highly Cited
2012
Many different definitions for multidrug-resistant (MDR), extensively drug-resistant (XDR) and pandrug-resistant (PDR) bacteria… Expand
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Review
2009
Review
2009
Although antibiotics have been used in large quantities for some decades, until recently the existence of these substances in the… Expand
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Review
2006
Review
2006
Effective treatment of metastatic cancers usually requires the use of toxic chemotherapy. In most cases, multiple drugs are used… Expand
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Review
2002
Review
2002
Chemotherapeutics are the most effective treatment for metastatic tumours. However, the ability of cancer cells to become… Expand
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Highly Cited
2001
Highly Cited
2001
SUMMARY Tetracyclines were discovered in the 1940s and exhibited activity against a wide range of microorganisms including gram… Expand
Highly Cited
1996
Highly Cited
1996
Hematopoietic stem cells (HSC) are multipotent cells that reside in the bone marrow and replenish all adult hematopoietic… Expand
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Highly Cited
1994
Highly Cited
1994
ACTIVATED protein C (APC) is a serine protease with potent anti-coagulant properties, which is formed in blood on the endothelium… Expand
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Review
1993
Review
1993
Highly Cited
1992
Highly Cited
1992
The doxorubicin-selected lung cancer cell line H69AR is resistant to many chemotherapeutic agents. However, like most tumor… Expand