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Mitogen-Activated Protein Kinase 14

Known as: MAPK14 Mitogen Activated Protein Kinase, MAP Kinase, p38alpha, MAX Interacting Protein 2 
A 38-kDa mitogen-activated protein kinase that is abundantly expressed in a broad variety of cell types. It is involved in the regulation of cellular… 
National Institutes of Health

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In BloodMAP3K8 protein, humanMAPK14 geneMAPK14 wt Allele

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MAPK14 protein, human

Papers overview

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Highly Cited
2016
Highly Cited
2016
Cellular localization of NRF2 determines the self-renewal and osteogenic differentiation potential of human MSCs via the P53–SIRT1 axis
The Wnt inhibitor Dickkopf-1 (DKK-1) has been associated with the occurrence of bone metastases in osteotropic prostate cancer by… 
Highly Cited
2012
Highly Cited
2012
Toll-Like Receptor 4 and MYD88-Dependent Signaling Mechanisms of the Innate Immune System Are Essential for the Response to Lipopolysaccharide by Epithelial and Stromal Cells of the Bovine…
ABSTRACT Infection of the bovine endometrium with Gram-negative bacteria commonly causes uterine disease. Toll-like receptor 4… 
Highly Cited
2011
Highly Cited
2011
A Computational Approach to Finding Novel Targets for Existing Drugs
Repositioning existing drugs for new therapeutic uses is an efficient approach to drug discovery. We have developed a… 
Highly Cited
2007
Highly Cited
2007
Effects of Metformin on Bovine Granulosa Cells Steroidogenesis: Possible Involvement of Adenosine 5′ Monophosphate-Activated Protein Kinase (AMPK)1
Abstract In mammals, IGFs are important for the proliferation and steroidogenesis of ovarian cells. Metformin is an insulin… 
Highly Cited
2007
Highly Cited
2007
Complementation of placental defects and embryonic lethality by trophoblast-specific lentiviral gene transfer
Placental dysfunction underlies many complications during pregnancy, and better understanding of gene function during… 
Highly Cited
2004
Highly Cited
2004
Mitochondrial AKAP121 Binds and Targets Protein Tyrosine Phosphatase D1, a Novel Positive Regulator of src Signaling
ABSTRACT A-kinase anchor protein 121 (AKAP121) and its spliced isoform AKAP84 anchor protein kinase A (PKA) to the outer membrane… 
Highly Cited
2003
Highly Cited
2003
Feedback control of the protein kinase TAK1 by SAPK2a/p38α
TAB1, a subunit of the kinase TAK1, was phosphorylated by SAPK2a/p38α at Ser423, Thr431 and Ser438 in vitro. TAB1 became… 
Highly Cited
2002
Highly Cited
2002
Inhibition of SAPK2a/p38 prevents hnRNP A0 phosphorylation by MAPKAP‐K2 and its interaction with cytokine mRNAs
Lipopolysaccharide (LPS) stimulates production of inflammatory mediators, partly by stabilizing [interleukin‐6 (IL‐6… 
Highly Cited
2000
Highly Cited
2000
Synergistic activation of stress-activated protein kinase 1/c-Jun N-terminal kinase (SAPK1/JNK) isoforms by mitogen-activated protein kinase kinase 4 (MKK4) and MKK7.
Stress-activated protein kinase 1 (SAPK1), also called c-Jun N-terminal kinase (JNK), becomes activated in vivo in response to… 
Highly Cited
1996
Highly Cited
1996
The Dual Specificity Phosphatases M3/6 and MKP-3 Are Highly Selective for Inactivation of Distinct Mitogen-activated Protein Kinases*
The mitogen-activated protein (MAP) kinase family includes extracellular signal-regulated kinase (ERK), c-Jun NH2-terminal kinase… 
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