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MAPK14 wt Allele

Known as: Mitogen-Activated Protein Kinase 14 wt Allele, PRKM14, PRKM15 
Human MAPK14 wild-type allele is located within 6p21.3-p21.2 and is approximately 83 kb in length. This allele, which encodes mitogen-activated… 
National Institutes of Health

Related topics

Related topics

35 relations
6p21.3-p21.2ApoptosisB Cell Receptor Signaling PathwayB-Cell Immune Response Pathway

Broader (1)

MAPK14 gene

Papers overview

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2010
2010
LPA induces IL-6 secretion from aortic smooth muscle cells via an LPA1-regulated, PKC-dependent, and p38alpha-mediated pathway.
Lysophosphatidic acid (LPA) is a potent bioactive lysophospholipid. Accumulated evidence supports a role for LPA in inflammation… 
2008
2008
p38alpha-selective MAP kinase inhibitor reduces tumor growth in mouse xenograft models of multiple myeloma.
Multiple myeloma (MM) is a clonal plasma cell malignancy, which is currently incurable. Therefore, new mono- or combined therapy… 
Highly Cited
2007
Highly Cited
2007
Phosphatidylinositol Ether Lipid Analogues That Inhibit AKT Also Independently Activate the Stress Kinase, p38α, through MKK3/6-independent and -dependent Mechanisms*
Previously, we identified five active phosphatidylinositol ether lipid analogues (PIAs) that target the pleckstrin homology… 
2006
2006
TEF-1 and C/EBPbeta are major p38alpha MAPK-regulated transcription factors in proliferating cardiomyocytes.
p38 MAPKs (mitogen-activated protein kinases) play important roles in the regulation of cellular responses to environmental… 
2003
2003
TAB1beta (transforming growth factor-beta-activated protein kinase 1-binding protein 1beta ), a novel splicing variant of TAB1 that interacts with p38alpha but not TAK1.
The mitogen-activated protein kinases (MAPKs) play an important role in a variety of biological processes. Activation of MAPKs is… 
2003
2003
Ionizing radiation up-regulates cyclooxygenase-2 in I407 cells through p38 mitogen-activated protein kinase.
The epithelial cell line I407 up-regulates cyclooxygenase-2 (COX-2) mRNA and protein expression following ionizing radiation… 
2003
2003
N-Phenyl-N-purin-6-yl ureas: the design and synthesis of p38alpha MAP kinase inhibitors.
2002
2002
p38 MAPK mediates acid-induced transcription of PEPCK in LLC-PK(1)-FBPase(+) cells.
LLC-PK(1)-FBPase(+) cells are a gluconeogenic and pH-responsive renal proximal tubule-like cell line. On incubation with acidic… 
2000
2000
Cisplatin and UV radiation induce activation of the stress-activated protein kinase p38gamma in human melanoma cells.
The p38 alpha mitogen-activated protein kinase has been implicated in the cellular response to genotoxic agents. Here we show… 
Highly Cited
1999
Highly Cited
1999
Cloning and Characterization of RLPK, a Novel RSK-related Protein Kinase*
A novel protein kinase whose activity can be stimulated by mitogen in vivo was cloned and characterized. The cDNA of this gene… 
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