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Depression is common in dementia but the evidence base for appropriate drug treatment is sparse and equivocal. We… Expand Sleep and circadian rhythm disruption are frequently observed in patients with psychiatric disorders and neurodegenerative… Expand BACKGROUND
Conventional meta-analyses have shown inconsistent results for efficacy of second-generation antidepressants. We… Expand Editor's Note: This issue of In the Clinic has been updated. More than 30% of U.S. adults are obese (1). Generally defined as a… Expand OBJECTIVE
Few controlled studies have addressed the issue of which antidepressant medications should be recommended for… Expand OBJECTIVE
The purpose of this study was to compare the effectiveness and tolerability of tranylcypromine and combination… Expand STAR*D is a multisite, prospective, randomized, multistep clinical trial of outpatients with nonpsychotic major depressive… Expand Pruritus is a relatively rare but distressing symptom associated with cholestasis, renal failure, and malignancies. Medical… Expand The novel antidepressant mirtazapine has a dual mode of action. It is a noradrenergic and specific serotonergic antidepressant… Expand Mirtazapine is the first noradrenergic and specific serotonergic antidepressant (‘NaSSA’). It is rapidly and well absorbed from… Expand