Mirtazapine

Known as: Mirtazapina, 6-azamianserin, Mirtazapin 
A synthetic tetracyclic derivative of the piperazino-azepines with antidepressant activity. Although its mechanism of action is unknown, mirtazapine… (More)
National Institutes of Health

Related topics

Related topics

21 relations

Broader (4)

Adrenergic alpha-AntagonistsHistamine H1 AntagonistsMianserinTricyclic Antidepressive Agents
Adrenergic alpha1-Antagonists [MoA]Adrenergic alpha2-Antagonists [MoA]Depressive disorderDrug Allergy
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Narrower (5)

EsmirtazapineORG 3770Org 50081Remeron
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Papers overview

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2012
2012
[Mirtazapine versus other antidepressive agents for depression].
A Cochrane analysis compared efficacy and side effects of mirtazapine with other antidepressants. After six weeks of treatment no… (More)
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Review
2011
Review
2011
Sertraline or mirtazapine for depression in dementia (HTA-SADD): a randomised, multicentre, double-blind, placebo-controlled trial
BACKGROUND Depression is common in dementia but the evidence base for appropriate drug treatment is sparse and equivocal. We… (More)
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Highly Cited
2007
Highly Cited
2007
Clinical response and risk for reported suicidal ideation and suicide attempts in pediatric antidepressant treatment: a meta-analysis of randomized controlled trials.
CONTEXT The US Food and Drug Administration (FDA) has issued warnings that use of antidepressant medications poses a small but… (More)
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Highly Cited
2006
Highly Cited
2006
Tranylcypromine versus venlafaxine plus mirtazapine following three failed antidepressant medication trials for depression: a STAR*D report.
OBJECTIVE The purpose of this study was to compare the effectiveness and tolerability of tranylcypromine and combination… (More)
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Highly Cited
2006
Highly Cited
2006
A comparison of mirtazapine and nortriptyline following two consecutive failed medication treatments for depressed outpatients: a STAR*D report.
OBJECTIVE Few controlled studies have addressed the issue of which antidepressant medications should be recommended for… (More)
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Highly Cited
2005
Highly Cited
2005
The catechol-O-methyltransferase Val108/158Met polymorphism affects short-term treatment response to mirtazapine, but not to paroxetine in major depression
The catechol-O-methyltransferase (COMT) is a major degrading enzyme in the metabolic pathways of catecholaminergic… (More)
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Highly Cited
2005
Highly Cited
2005
Antinociceptive effects of the antidepressants amitriptyline, duloxetine, mirtazapine and citalopram in animal models of acute, persistent and neuropathic pain
The effects of acute, systemic administration of amitriptyline, duloxetine and mirtazapine (antidepressant drugs that variously… (More)
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2003
2003
Mirtazapine vs. placebo in posttraumatic stress disorder: a pilot trial
BACKGROUND Based on an earlier pilot study, as well as a theoretical consideration of its mechanism of action, we undertook a… (More)
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2000
2000
Mirtazapine compared with paroxetine in major depression.
BACKGROUND The aim was to compare the efficacy and tolerability of mirtazapine with those of paroxetine. METHOD 275 outpatients… (More)
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Review
1997
Review
1997
Mirtazapine: an antidepressant with noradrenergic and specific serotonergic effects.
Mirtazapine is a unique antidepressant that refines the specificity of effects on noradrenergic and serotonergic systems. It is… (More)
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