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ORG 3770

Known as: ORG-3770 
National Institutes of Health

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Related topics

1 relation

Broader (1)

Mirtazapine

Papers overview

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Highly Cited
2004
Highly Cited
2004
Effect of the antidepressant Org 3770 on human sleep
SummaryThe effect of a single dose (30 mg) of Org 3770 (metirzapine) on human sleep was assessed in a double blind, placebo… 
2004
2004
An alpha2 adrenoceptor antagonist, Org 3770, enhances nocturnal melatonin secretion in man
Nocturnal plasma melatonin concentration was significantly increased in ten normal volunteers following the administration of an… 
Review
1995
Review
1995
Noradrenergic modulation of central serotonergic neurotransmission: acute and long-term actions of mirtazapine
Mirtazapine (Org3770, Remeron) is a new α2-adrenoceptor antagonist which is an effective antidepressant drug. An in vivo… 
Highly Cited
1995
Highly Cited
1995
The Selective α2-Adrenoceptor Antagonist Mirtazapine (Org 3770) Enhances Noradrenergic and 5-HT1A-Mediated Serotonergic Neurotransmission
SummaryMirtazapine (Org 3770) is a selective antagonist at α2-adrenergic auto- and heteroreceptors, which are involved in… 
1995
1995
A double-blind comparison of Org 3770, amitriptyline, and placebo in major depression.
  • J. Bremner
  • Journal of Clinical Psychiatry
  • 1995
  • Corpus ID: 23042946
BACKGROUND A 6-week, double-blind, dose titration study was performed to evaluate efficacy and safety of the new antidepressant… 
Highly Cited
1995
Highly Cited
1995
A double-blind placebo-controlled study of Org 3770 in depressed outpatients.
1994
1994
The alpha 2-adrenoceptor antagonist Org 3770 enhances serotonin transmission in vivo.
The antidepressant properties of Org 3770 (1,2,3,4,10,14b-hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3- c][2]benzazepine) may be… 
1989
1989
Actions and interactions of psychotropic drugs on human performance and mood: single doses of ORG 3770, amitriptyline, and diazepam.
Actions and interactions of two antidepressants and diazepam on human skilled performance and mood were studied in a randomized… 
Highly Cited
1988
Highly Cited
1988
Neurochemical and autonomic pharmacological profiles of the 6-aza-analogue of mianserin, org 3770 and its enantiomers
1985
1985
A double‐blind group comparative study using the new anti‐depressant Org 3770, placebo and diazepam in patients with expected insomnia and anxiety before elective gynaecological surgery
ABSTRACT Two hundred and fifty female patients about to undergo elective gynaecological surgery, were randomly allocated to a… 
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