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Milrinone

Known as: Milrinona, 1,6-Dihydro-2-methyl-6-oxo(3,4'-bipyridine)-5-carbonitrile, Milrinone [Chemical/Ingredient] 
A positive inotropic cardiotonic agent with vasodilator properties. It inhibits cAMP phosphodiesterase type 3 activity in myocardium and vascular… 
National Institutes of Health

Related topics

Related topics

22 relations
100 ML Milrinone Lactate 0.2 MG/ML InjectionCongestive heart failureDrug toxicityHypersensitivity

Broader (5)

Cardiotonic AgentsPhosphodiesterase 3 InhibitorsPlatelet Aggregation InhibitorsPyridones

Narrower (3)

CorotropeMilrinone LactatePrimacor

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
Levosimendan is superior to milrinone and dobutamine in selectively increasing microvascular gastric mucosal oxygenation in dogs*
Objective:The effect of levosimendan, a novel inotropic vasodilator (inodilator), on the microvascular gastric mucosal hemoglobin… 
Review
2005
Review
2005
Overview of randomized clinical trials in acute heart failure syndromes.
Highly Cited
2001
Highly Cited
2001
Sildenafil (viagra) facilitates weaning of inhaled nitric oxide following placement of a biventricular-assist device.
Review
2000
Review
2000
Outpatient parenteral inotropic therapy for advanced heart failure.
Highly Cited
1997
Highly Cited
1997
The Effect of Milrinone on Hemodynamics and Left Ventricular Function After Emergence from Cardiopulmonary Bypass
Although milrinone effectively increases cardiac function, few studies have specifically evaluated its efficacy during cardiac… 
1991
1991
Selective inhibition of cGMP-inhibited and cGMP-noninhibited cyclic nucleotide phosphodiesterases and relaxation of rat aorta.
Review
1989
Review
1989
Biochemical aspects of inhibition of cardiovascular low (Km) cyclic adenosine monophosphate phosphodiesterase.
Highly Cited
1989
Highly Cited
1989
Effect of phosphodiesterase inhibition on myocardial oxygen consumption and coronary blood flow.
Highly Cited
1986
Highly Cited
1986
Separation of the direct myocardial and vasodilator actions of milrinone administered by an intracoronary infusion technique.
To determine the relative contributions of milrinone's positive inotropic and vasodilator actions in patients with severe… 
Highly Cited
1986
Highly Cited
1986
Pharmacology of the bipyridines: amrinone and milrinone.
: The cardiovascular bipyridines amrinone and milrinone are positive inotropic agents with vasodilator properties. When their… 
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