Milrinone

Known as: Milrinona, 1,6-Dihydro-2-methyl-6-oxo(3,4'-bipyridine)-5-carbonitrile, Milrinone [Chemical/Ingredient] 
A positive inotropic cardiotonic agent with vasodilator properties. It inhibits cAMP phosphodiesterase type 3 activity in myocardium and vascular… (More)
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
BACKGROUND Admission measures of renal function (blood urea nitrogen [BUN], estimated glomerular filtration rate [eGFR]) in… (More)
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2006
2006
Current standard therapy for persistent pulmonary hypertension of the newborn (PPHN) consists of optimal lung inflation… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND The prognostic value of serum sodium in patients hospitalized for worsening heart failure has not been well defined… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Low cardiac output syndrome (LCOS), affecting up to 25% of neonates and young children after cardiac surgery… (More)
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Highly Cited
2003
Highly Cited
2003
OBJECTIVES The goal of this study was to assess the interaction between heart failure (HF) etiology and response to milrinone in… (More)
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1999
1999
BACKGROUND Milrinone has been shown to increase cardiac output in children after cardiac surgery, but pharmacokinetic analysis… (More)
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Highly Cited
1995
Highly Cited
1995
OBJECTIVE To evaluate the hemodynamic effects of intravenous milrinone in neonates with low cardiac output after cardiac surgery… (More)
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Highly Cited
1991
Highly Cited
1991
BACKGROUND Milrinone, a phosphodiesterase inhibitor, enhances cardiac contractility by increasing intracellular levels of cyclic… (More)
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Highly Cited
1989
Highly Cited
1989
We randomly assigned 230 patients in sinus rhythm with moderately severe heart failure to treatment with digoxin, milrinone, both… (More)
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1986
1986
The cardiovascular bipyridines amrinone and milrinone are positive inotropic agents with vasodilator properties. When their… (More)
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