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Microsomal Epoxide Hydrolase
Known as:
Epoxide Hydroxylase 1, Microsomal (Xenobiotic)
, EC 3.3.2.9
, Epoxide Hydroxylase 1, Microsomal
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Epoxide hydrolase 1 (455 aa, ~53 kDa) is encoded by the human EPHX1 gene. This protein is involved in the hydrolysis of cyclic organic compounds.
National Institutes of Health
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Related topics
Related topics
9 relations
EPHX1 gene
EPHX1 wt Allele
Enzyme Gene
Homo sapiens
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Broader (1)
Epoxide hydrolase
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2009
Review
2009
Mammalian epoxide hydrolases in xenobiotic metabolism and signalling
Martina Decker
,
M. Arand
,
A. Cronin
Archives of Toxicology
2009
Corpus ID: 25419954
Epoxide hydrolases catalyse the hydrolysis of electrophilic—and therefore potentially genotoxic—epoxides to the corresponding…
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Highly Cited
2000
Highly Cited
2000
Controlling Interchain Interactions in Conjugated Polymers: The Effects of Chain Morphology on Exciton-Exciton Annihilation and Aggregation in MEH-PPV Films
Thuc‐Quyen Nguyen
,
I. Martini
,
Jei Liu
,
B. Schwartz
2000
Corpus ID: 31516641
The presence of interchain species in the photophysics of conjugated polymer films has been the subject of a great deal of…
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Highly Cited
1999
Highly Cited
1999
Targeted Disruption of the Microsomal Epoxide Hydrolase Gene
M. Miyata
,
G. Kudo
,
+5 authors
F. Gonzalez
Journal of Biological Chemistry
1999
Corpus ID: 12351641
Microsomal epoxide hydrolase (mEH) is a conserved enzyme that is known to hydrolyze many drugs and carcinogens, and a few…
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Review
1998
Review
1998
Polymorphisms of N-acetyltransferases, glutathione S-transferases, microsomal epoxide hydrolase and sulfotransferases: influence on cancer susceptibility.
J. Hengstler
,
M. Arand
,
M. Herrero
,
F. Oesch
Recent results in cancer research. Fortschritte…
1998
Corpus ID: 42816836
It has become clear that several polymorphisms of human drug-metabolizing enzymes influence an individual's susceptibility for…
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Highly Cited
1996
Highly Cited
1996
Charge separation and transport in conjugated-polymer/semiconductor-nanocrystal composites studied by photoluminescence quenching and photoconductivity.
N. Greenham
,
Xiaogang Peng
,
A. Alivisatos
Physical Review B (Condensed Matter)
1996
Corpus ID: 32059467
We study the processes of charge separation and transport in composite materials formed by mixing cadmium selenide or cadmium…
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Highly Cited
1996
Highly Cited
1996
Combined analysis of inherited polymorphisms in arylamine N-acetyltransferase 2, glutathione S-transferases M1 and T1, microsomal epoxide hydrolase, and cytochrome P450 enzymes as modulators of…
J. Brockmöller
,
I. Cascorbi
,
R. Kerb
,
I. Roots
Cancer Research
1996
Corpus ID: 17660380
Foreign compound-metabolizing enzymes may modify the risk of chemically induced cancer. We wanted to examine enzymes with…
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Highly Cited
1996
Highly Cited
1996
Direct measurement of conjugated polymer electronic excitation energies using metal/polymer/metal structures.
I. Campbell
,
T. Hagler
,
Darryl L. Smith
,
J. Ferraris
Physical Review Letters
1996
Corpus ID: 41206550
We report electroabsorption measurements of built-in electric fields and internal photoemission measurements of Schottky barriers…
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Highly Cited
1994
Highly Cited
1994
Human microsomal epoxide hydrolase: genetic polymorphism and functional expression in vitro of amino acid variants.
C. Hassett
,
Lauri D. Aicher
,
J. S. Sidhu
,
C. Omiecinski
Human Molecular Genetics
1994
Corpus ID: 12043336
Human microsomal epoxide hydrolase (mEH) is a biotransformation enzyme that metabolizes reactive epoxide intermediates to more…
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Highly Cited
1980
Highly Cited
1980
Increase of NAD(P)H:quinone reductase by dietary antioxidants: possible role in protection against carcinogenesis and toxicity.
A. Benson
,
Markus J. Hunkeler
,
P. Talalay
Proceedings of the National Academy of Sciences…
1980
Corpus ID: 33540077
2(3)-tert-Butyl-4-hydroxyanisole (BHA) is one of several widely used antioxidant food additives that protect against chemical…
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Review
1973
Review
1973
Mammalian epoxide hydrases: inducible enzymes catalysing the inactivation of carcinogenic and cytotoxic metabolites derived from aromatic and olefinic compounds.
F. Oesch
Xenobiotica; the fate of foreign compounds in…
1973
Corpus ID: 32500968
Abstract1. Several aromatic and olefinic compounds are converted to intermediate arene and alkene oxides by mammalian mono…
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