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Microsomal Epoxide Hydrolase

Known as: Epoxide Hydroxylase 1, Microsomal (Xenobiotic), EC 3.3.2.9, Epoxide Hydroxylase 1, Microsomal 
Epoxide hydrolase 1 (455 aa, ~53 kDa) is encoded by the human EPHX1 gene. This protein is involved in the hydrolysis of cyclic organic compounds.
National Institutes of Health

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9 relations
EPHX1 geneEPHX1 wt AlleleEnzyme GeneHomo sapiens

Broader (1)

Epoxide hydrolase

Papers overview

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Highly Cited
2009
Highly Cited
2009
Modeling the dynamics of chromophores in conjugated polymers: the case of poly(2-methoxy-5-(2'-ethylhexyl)oxy 1,4-phenylene vinylene) (MEH-PPV).
By combining force-field approaches to quantum-chemical techniques, we have explored the influence of conformational changes on… 
Highly Cited
2008
Highly Cited
2008
Fabrication of conjugated polymer nanowires by edge lithography.
This paper describes the fabrication of conjugated polymer nanowires by a three stage process: (i) spin-coating a composite film… 
2005
2005
Controlling optical properties and interchain interactions in semiconducting polymers by encapsulation in periodic nanoporous silicas with different pore sizes.
The photophysics of MEH-PPV incorporated into the pores of periodic silica hosts has been investigated in an effort to understand… 
2005
2005
Genetic analysis of microsomal epoxide hydrolase gene and its association with lung cancer risk
The human microsomal epoxide hydrolase (EH) gene contains polymorphic alleles, which may be linked to increased risk for tobacco… 
2003
2003
Male mice deficient in microsomal epoxide hydrolase are not susceptible to benzene-induced toxicity.
Enzymes involved in benzene metabolism are likely genetic determinants of benzene-induced toxicity. Polymorphisms in human… 
Highly Cited
2000
Highly Cited
2000
Origin of line broadening in the electronic absorption spectra of conjugated polymers: Three-pulse-echo studies of MEH-PPV in toluene
Integrated three-pulse stimulated echo peak shift data are compared for N,N-bis-dimethylphenyl-2,4,6,8perylenetetracarbonyl… 
Highly Cited
1996
Highly Cited
1996
Absorption-detected magnetic-resonance studies of photoexcitations in conjugated-polymer/C60 composites.
Photoexcitations in poly[2-methoxy-5-(${2}^{\ensuremath{'}}$-ethyl-hexyloxy)-p-phenylene vinylene] (MEH-PPV) and composites of… 
Highly Cited
1976
Highly Cited
1976
Epoxides derived from various polycyclic hydrocarbons as substrates of homogeneous and microsome-bound epoxide hydratase. A general assay and kinetic properties.
A general assay for epoxide hydratase using epoxides derived from polycyclic aromatic hydrocarbons as substrates is described… 
Review
1976
Review
1976
Antibodies against homogeneous epoxide hydratase provide evidence for a single enzyme hydrating styrene oxide and benz(a)pyrene 4,5-oxide
THE microsomal enzyme epoxide hydratase (EC 4.2.1.63) is potentially important in the inactivation of metabolically produced… 
Highly Cited
1976
Highly Cited
1976
Prevention of benzo(a)pyrene‐induced mutagenicity by homogeneous epoxide hydratase
Benzo(a)pyrene and benz(a)anthrancene which, in contrast to the K‐region epoxides benzo(a)pyrene 4,5‐oxide and benz(a)anthracene… 
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