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Epoxide hydrolase

Known as: Epoxide Hydratases, Hydratases, Epoxide, Hydrases, Epoxide 
Enzymes that catalyze reversibly the formation of an epoxide or arene oxide from a glycol or aromatic diol, respectively.
National Institutes of Health

Related topics

Related topics

20 relations

Narrower (10)

9,10-Epoxypalmitic Acid HydraseAlp1U protein, Streptomyces ambofaciensMicrosomal Epoxide HydrolaseStyrene Epoxide Hydrolase
EPHX1 geneIn BloodProcess of secretionantagonists & inhibitors

Broader (1)

ether hydrolase

Papers overview

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1988
1988
Synthesis of 2'-epi-distichonic acid A, an iron-chelating amino acid derivative.
2'-epi-Distichonic acid A (4b), an iron-chelating amino acid derivative was synthesized starting from L-vinylglycine epoxide (6b… 
1983
1983
Metabolic activation of chrysene in mouse skin: evidence for the involvement of a triol-epoxide.
All three possible dihydrodiols of chrysene and a chrysene triol, formed from the further metabolism of the chrysene-1,2-diol… 
1983
1983
Species differences in cytochromes P-450 and epoxide hydrolase: comparisons of xenobiotic-induced hepatic microsomal polypeptides in hamsters and rats.
Cytochromes P-450 and epoxide hydrolase in hamsters were studied by using two-dimensional gel electrophoresis of hepatic… 
1980
1980
Reduction of epoxy derivatives of benzo(a)pyrene by microsomal cytochrome P-450.
Abstract Benzo( a )pyrene 4,5-oxide was rapidly reduced to benzo( a )pyrene by rat liver microsomes in the presence of reduced… 
1980
1980
Quantiation of epoxide hydrolase released from hyperplastic nodule and hepatoma microsomes.
Incubation conditions have been established for the release of epoxide hydrolase from rat liver hyperplastic nodule and hepatoma… 
1979
1979
Metabolism and excretion of benzo(a)pyrene 4,5-oxide by the isolated perfused rat liver.
Benzo(a)pyrene 4,5-oxide was metabolized in the isolated perfused rat liver by epoxide hydrase and glutathione S-transferases to… 
Highly Cited
1978
Highly Cited
1978
Reduced nicotinamide adenine dinucleotide phosphate-dependent formation of 2,3-dihydro-2,3-dihydroxyaflatoxin B1 from aflatoxin B1 by hepatic microsomes.
2,3-Dihydro-2,3-dihydroxyaflatoxin B1 (dihydrodiol) was formed as a major metabolite in the incubation of aflatoxin B1 with rat… 
Review
1977
Review
1977
Characterization of rat lung epoxide (styrene oxide) hydrase with a modified radioactive assay of improved sensitivity.
The epoxide hydrase assay developed by Oesch et al. (Biochim. Biophys. Acta, 227: 685-691, 1971) using [3H]styrene oxide as… 
1976
1976
Etiologic related studies of ultraviolet light-mediated carcinogenesis.
Comparisons were made of cholesterol-5alpha, 6alpha-epoxide (CAE) levels in skin of hairless mice maintained on a regular or… 
1975
1975
Inhibition of benzo(alpha)pyrene metabolism catalyzed by mouse and hamster lung microsomes.
Induced and constitutive microsomal enzymes of mouse and hamster lungs catalyze both the hydroxylation of benzo(alpha)pyrene and…