Micrococcal Nuclease

Known as: Nuclease, Micrococcal, Micrococcal Nuclease [Chemical/Ingredient], TNase 
An enzyme that catalyzes the endonucleolytic cleavage to 3'-phosphomononucleotide and 3'-phospholigonucleotide end-products. It can cause hydrolysis… (More)
National Institutes of Health

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Highly Cited
2011
Highly Cited
2011
Nucleases that cleave unique genomic sequences in living cells can be used for targeted gene editing and mutagenesis. Here we… (More)
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2010
2010
Eukaryotic genomes are packed into chromatin, whose basic repeating unit is the nucleosome. Nucleosome positioning is a widely… (More)
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Highly Cited
2009
Highly Cited
2009
Nucleosome organization is critical for gene regulation. In living cells this organization is determined by multiple factors… (More)
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Highly Cited
2003
Highly Cited
2003
RNA interference (RNAi) regulates gene expression by the cleavage of messenger RNA, by mRNA degradation and by preventing protein… (More)
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Highly Cited
1992
Highly Cited
1992
Synthetic oligonucleotide primers of 21 and 24 bases, respectively, were used in the polymerase chain reaction (PCR) to amplify a… (More)
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Highly Cited
1990
Highly Cited
1990
Cell death by apoptosis mediates several important physiologic and pathologic processes and appears to be intrinsically… (More)
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Highly Cited
1989
Highly Cited
1989
This paper describes the use of novel two-dimensional nuclear magnetic resonance (NMR) pulse sequences to provide insight into… (More)
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Highly Cited
1981
Highly Cited
1981
Micrococcal nuclease is shown to cleave DNA under conditions of partial digestion in a specific manner. Sequences of the type 5… (More)
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Highly Cited
1981
Highly Cited
1981
The substrate specificity of micrococcal nuclease (EC 3.1.4.7.) has been studied. The enzyme recognises features of nucleotide… (More)
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Highly Cited
1976
Highly Cited
1976
A simple method is described for converting a standard rabbit reticulocyte cell-free extract (lysate) into an mRNA-dependent… (More)
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