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nuclease

Known as: nucleases 
 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Genome editing with CRISPR/Cas has rapidly gained popularity. Base editing, a new CRISPR/Cas-based approach, can precisely… Expand
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Review
2019
Review
2019
Oligonucleotide-based agents have the potential to treat or cure almost any disease, and are one of the key therapeutic drug… Expand
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Review
2019
Review
2019
  • Hong-xia Zhang, Ying Zhang, H. Yin
  • Molecular therapy : the journal of the American…
  • 2019
  • Corpus ID: 73471747
Genome-editing technologies based on programmable nucleases have significantly broadened our ability to make precise and direct… Expand
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Review
2019
Review
2019
Nonsense-mediated mRNA decay (NMD), which is arguably the best-characterized translation-dependent regulatory pathway in mammals… Expand
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Review
2018
Review
2018
The CRISPR/Cas technology has recently become the tool of choice for targeted genome modification in plants and beyond. Although… Expand
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Highly Cited
2014
Highly Cited
2014
Clustered, regularly interspaced, short palindromic repeat (CRISPR) RNA-guided nucleases (RGNs) are highly efficient genome… Expand
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Highly Cited
2013
Highly Cited
2013
The Streptococcus pyogenes Cas9 (SpCas9) nuclease can be efficiently targeted to genomic loci by means of single-guide RNAs… Expand
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Highly Cited
2013
Highly Cited
2013
Genome Editing Clustered regularly interspaced short palindromic repeats (CRISPR) function as part of an adaptive immune system… Expand
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Highly Cited
2011
Highly Cited
2011
Nucleases that cleave unique genomic sequences in living cells can be used for targeted gene editing and mutagenesis. Here we… Expand
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Highly Cited
1999
Highly Cited
1999
  • K. Livak
  • Genetic analysis : biomolecular engineering
  • 1999
  • Corpus ID: 21526728
Large-scale screening for known polymorphisms will require techniques with few steps and the ability to automate each of these… Expand
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