endonuclease

Known as: Endonucleases, Endonucleases [Chemical/Ingredient] 
Enzymes that catalyze the hydrolysis of the internal bonds and thereby the formation of polynucleotides or oligonucleotides from ribo- or… (More)
National Institutes of Health

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Highly Cited
2014
Highly Cited
2014
The clustered regularly interspaced short palindromic repeats (CRISPR)-associated enzyme Cas9 is an RNA-guided endonuclease that… (More)
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Highly Cited
2013
Highly Cited
2013
We employ the CRISPR-Cas system of Streptococcus pyogenes as programmable RNA-guided endonucleases (RGENs) to cleave DNA in a… (More)
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Highly Cited
2012
Highly Cited
2012
Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated (Cas) systems provide bacteria and archaea… (More)
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Highly Cited
1996
Highly Cited
1996
Human L1 elements are highly abundant poly(A) (non-LTR) retrotransposons whose second open reading frame (ORF2) encodes a reverse… (More)
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Highly Cited
1990
Highly Cited
1990
Cell death by apoptosis mediates several important physiologic and pathologic processes and appears to be intrinsically… (More)
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Highly Cited
1987
Highly Cited
1987
We previously developed a cladistic approach to identify subsets of haplotypes defined by restriction endonuclease mapping or DNA… (More)
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Highly Cited
1983
Highly Cited
1983
A technique for conveniently radiolabeling DNA restriction endonuclease fragments to high specific activity is described. DNA… (More)
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Highly Cited
1980
Highly Cited
1980
In near-physiological concentrations, glucocorticoid hormones cause the death of several types of normal and neoplastic lymphoid… (More)
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Highly Cited
1980
Highly Cited
1980
A method is presented for the rapid isolation of high molecular weight plant DNA (50,000 base pairs or more in length) which is… (More)
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Highly Cited
1979
Highly Cited
1979
A mathematical model for the evolutionary change of restriction sites in mitochondrial DNA is developed. Formulas based on this… (More)
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