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Cas9 protein, Francisella novicida

Known as: Cas9 endonuclease, Francisella novicida, FnCas9 protein, F novicida 
 
National Institutes of Health

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Highly Cited
2017
Highly Cited
2017
Several CRISPR-Cas9 orthologues have been used for genome editing. Here, we present the smallest Cas9 orthologue characterized to… Expand
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Review
2017
Review
2017
Research on fungal pathogens with the aim to identify virulence determinants strictly relies on the generation of defined… Expand
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Highly Cited
2016
Highly Cited
2016
The β-haemoglobinopathies, such as sickle cell disease and β-thalassaemia, are caused by mutations in the β-globin (HBB) gene and… Expand
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Highly Cited
2016
Highly Cited
2016
CRISPR (clustered regularly interspaced short palindromic repeats)/Cas9 system, which is a newly developed technology for… Expand
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Highly Cited
2015
Highly Cited
2015
Although CRISPR-Cas9 nucleases are widely used for genome editing, the range of sequences that Cas9 can recognize is constrained… Expand
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Highly Cited
2015
Highly Cited
2015
We describe an engineered photoactivatable Cas9 (paCas9) that enables optogenetic control of CRISPR-Cas9 genome editing in human… Expand
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Highly Cited
2015
Highly Cited
2015
Chronic hepatitis B virus (HBV) infection causes liver cirrhosis and hepatocellular carcinoma and remains a serious health… Expand
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Highly Cited
2014
Highly Cited
2014
BackgroundCRISPR-Cas9 is a revolutionary genome editing technique that allows for efficient and directed alterations of the… Expand
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Highly Cited
2013
Highly Cited
2013
The type II CRISPR/Cas system from Streptococcus pyogenes and its simplified derivative, the Cas9/single guide RNA (sgRNA) system… Expand
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Highly Cited
2013
Highly Cited
2013
Precise and straightforward methods to edit the plant genome are much needed for functional genomics and crop improvement… Expand
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