Organization of the constant-region gene family of the mouse immunoglobulin heavy chain

@article{Shimizu1982OrganizationOT,
  title={Organization of the constant-region gene family of the mouse immunoglobulin heavy chain},
  author={Akira Shimizu and Naoki Takahashi and Yoshio Yaoita and Tasuku Honjo},
  journal={Cell},
  year={1982},
  volume={28},
  pages={499-506}
}
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5′ Flanking region of immunoglobulin heavy chain constant region genes displays length heterogeneity in germlines of inbred mouse strains
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TLDR
The lack of homology between this C alpha sequence and sequences reported for the C gamma 1 and C gamma 2b switch sites suggests that heavy chain switching is mediated by class-specific recognition sequences and, presumably, class- specific regulatory mechanisms.
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