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Mice, Knockout

Known as: Mice, Knock-out, Knockout Mice, Knock-out Mice 
Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology… Expand
National Institutes of Health

Papers overview

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Review
2016
Review
2016
MicroRNAs (miRNAs) are highly conserved noncoding RNAs of about 19-25 nucleotides. Through specifically pairing with… Expand
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Highly Cited
2014
Highly Cited
2014
A major challenge in human genetics is to devise a systematic strategy to integrate disease-associated variants with diverse… Expand
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Highly Cited
2013
Highly Cited
2013
Many studies are uncovering functional roles for long noncoding RNAs (lncRNAs), yet few have been tested for in vivo relevance… Expand
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Highly Cited
2002
Highly Cited
2002
Fragile-X syndrome is a common form of mental retardation resulting from the inability to produce the fragile-X mental… Expand
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Highly Cited
2001
Highly Cited
2001
There is considerable evidence that osteoclasts are involved in the pathogenesis of focal bone erosion in rheumatoid arthritis… Expand
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Highly Cited
2000
Highly Cited
2000
Sur1 knockout mouse β-cells lack KATP channels and show spontaneous Ca2+ action potentials equivalent to those seen in patients… Expand
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Highly Cited
2000
Highly Cited
2000
Most previous studies of atherosclerosis in hyperlipidemic mouse models have focused their investigations on lesions within the… Expand
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Highly Cited
1999
Highly Cited
1999
Fragile X syndrome is an X-linked form of mental retardation resulting from the absence of expression of the fragile X mental… Expand
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Highly Cited
1997
Highly Cited
1997
Aquaporin-4 (AQP4) is a mercurial-insensitive, water-selective channel that is expressed in astroglia and basolateral plasma… Expand
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Highly Cited
1995
Highly Cited
1995
BAX, a heterodimeric partner of BCL2, counters BCL2 and promotes apoptosis in gain-of-function experiments. A Bax knockout mouse… Expand
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