Gene Knockout Techniques

Known as: Techniques, Gene Knock-Out, Technique, Gene Knockout, Outs, Gene Knock 
Techniques to alter a gene sequence that result in an inactivated gene, or one in which the expression can be inactivated at a chosen time during… (More)
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Several recent studies in a number of model systems including zebrafish, Arabidopsis, and mouse have revealed phenotypic… (More)
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Highly Cited
2012
Highly Cited
2012
Transcription activator-like effector nucleases (TALENs) are programmable nucleases that join FokI endonuclease with the modular… (More)
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Highly Cited
2008
Highly Cited
2008
Gene knockout is the most powerful tool for determining gene function or permanently modifying the phenotypic characteristics of… (More)
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Review
2008
Review
2008
The LDL receptor-related protein (originally called LRP, but now referred to as LRP1) is a large endocytic receptor that is… (More)
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Highly Cited
2006
Highly Cited
2006
We have systematically made a set of precisely defined, single-gene deletions of all nonessential genes in Escherichia coli K-12… (More)
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Highly Cited
2006
Highly Cited
2006
The low rate of homologous recombination exhibited by wild-type strains of filamentous fungi has hindered development of high… (More)
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Highly Cited
2003
Highly Cited
2003
The advent of genome-scale models of metabolism has laid the foundation for the development of computational procedures for… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND Survivin is a mammalian protein that carries a motif typical of the inhibitor of apoptosis (IAP)proteins, first… (More)
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Highly Cited
2000
Highly Cited
2000
It has been shown recently that matrix metalloproteinases (MMPs) are elevated after cerebral ischemia. In the current study, we… (More)
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Highly Cited
1998
Highly Cited
1998
Hereditary hemochromatosis (HH) is a common autosomal recessive disease characterized by increased iron absorption and… (More)
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