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Metiamide

Known as: Metiamide [Chemical/Ingredient], Thiourea, N-methyl-N'-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)- 
A histamine H2 receptor antagonist that is used as an anti-ulcer agent.
National Institutes of Health

Related topics

Related topics

9 relations

Broader (2)

Anti-Ulcer AgentHistamine H2 Antagonists
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

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Highly Cited
1980
Highly Cited
1980
Comparison of methionine-enkephalin and morphine in the stimulation of gastric acid secretion in the dog.
1980
1980
Randomised open controlled trial of colloidal bismuth subcitrate tablets and cimetidine in the treatment of duodenal ulcer.
In a study of 28 outpatients with endoscopically proven duodenal ulcers, 14 patients (with a total of 15 ulcers) were treated… 
Highly Cited
1979
Highly Cited
1979
Stimulation of alkaline secretion in amphibian-isolated gastric mucosa by 16,16-dimethyl PGE2 and PGF2 alpha. A proposed explanation for some of the cytoprotective actions of prostaglandins.
Highly Cited
1979
Highly Cited
1979
Effects of Antiinflammatory Agents and Prostaglandins on Acid and Bicarbonate Secretions in the Amphibian-Isolated Gastric Mucosa
Highly Cited
1978
Highly Cited
1978
Histamine suppression of human lymphocyte responses to mitogens.
1978
1978
Clonidine-induced hypotension: Further evidence for a central interaction with histamine H2 receptor antagonists in the rat
Highly Cited
1977
Highly Cited
1977
The in vitro effects of histamine and metiamide on neutrophil motility and their relationship to intracellular cyclic nucleotide levels.
Histamine at concentrations of 1 x 10(-5) M to 5 x 10(-5) M consistently increased neutrophil movement as measured in Boyden… 
Highly Cited
1976
Highly Cited
1976
Release of prostaglandins from healthy and sensitized guinea-pig lung and trachea by histamine.
Highly Cited
1976
Highly Cited
1976
THE INFLUENCE OF HISTAMINE ON EPITHELIAL CELL PROLIFERATION IN THE JEJUNUM OF THE RAT
1. The influence of histamine and histamine receptor blockade on the mitotic rate in epithelial cell proliferation in epithelial… 
1974
1974
Gastric Response to Metiamide
Metiamide greatly reduced pentagastrin-stimulated and overnight secretion of acid and pepsin in 11 patients with duodenal ulcer… 
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