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Metiamide

Known as: Metiamide [Chemical/Ingredient], Thiourea, N-methyl-N'-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)- 
A histamine H2 receptor antagonist that is used as an anti-ulcer agent.
National Institutes of Health

Related topics

Related topics

9 relations

Broader (2)

Anti-Ulcer AgentHistamine H2 Antagonists
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

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Highly Cited
1987
Highly Cited
1987
Enhancement by parainfluenza 3 infection of contractile responses to substance P and capsaicin in airway smooth muscle from the guinea pig.
Guinea pigs were inoculated by nasal insufflation with parainfluenza 3 (P-3) or virus growth medium 4 days before performing in… 
1985
1985
Effect of diet particle size and feeding of H2-receptor antagonists on gastric ulcers in swine.
Four experiments were conducted to evaluate the effect of diet and the administration of H2-antagonists in feed on gastric ulcer… 
1984
1984
Flavonoid-induced delay in the small intestinal transit: possible mechanism of action.
Three flavonoids viz: gossypin, epicatechin and hydroxyethyl rutosides were evaluated for their effect on small intestinal… 
1977
1977
Histamine Receptors in the Coronary Circulation of the Dog: Effects of Mepyramine and Metiamide on Responses to Histamine Infusions
The effect of histamine on coronary blood flow (CBF) was studied in anaesthetized greyhounds. CBF and systemic blood pressure… 
1977
1977
Absence of blocking effect of burimamide and metiamide on positive chronotropic and inotropic responses to histamine in isolated dog atrium.
When histamine was injected into the sinus node artery of isolated dog atrium perfused with arterial blood led from a carotid… 
1975
1975
Aspects of the effect of metiamide on pentagastrin-stimulated and basal gastric secretion of acid and pepsin in man.
This study has examined the inhibition produced by metiamide on the gastric secretion of acid and pepsin in 13 patients with… 
1975
1975
Effect of metiamide on acid secretion from isolated kitten fundic mucosa.
Isolated kitten fundic mucosa demonstrates low rates of spontaneous acid secretion in vitro when bathed in Krebs-Henseleit… 
1974
1974
Comparison effects of metiamide and atropine on gastric and pancreatic secretion and peptic ulcer formation in cat.
In conscious cats with chronic gastric and pancreatic fistulas, the actions of metiamide, a histamine H2-receΡtor antagonist, was… 
1974
1974
Effect of metiamide, a histamine H2-receptor antagonist, on gastric response to histamine, pentagastrin, insulin, and peptone meal in man
The action of metiamide on histamine-, and pentagastrin-, insulin-, and meal-induced maximal gastric secretion was studied in six… 
1974
1974
Effect of metiamide, a histamine antagonist of H2-receptors, on acid secretion of isolated canine stomach perfused with homologous blood.
The totally isolated canine stomach, perfused with homologous blood, was used to study the inhibitory action of metiamide, a…