Methiothepin

Known as: Piperazine, 1-(10,11-dihydro-8-(methylthio)dibenzo(b,f)thiepin-10-yl)-4-methyl-, Methiothepin [Chemical/Ingredient], Metitepine 
A serotonin receptor antagonist in the CENTRAL NERVOUS SYSTEM used as an antipsychotic.
National Institutes of Health

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Highly Cited
2003
Highly Cited
2003
Extracts of the rhizome of black cohosh [Actaea racemosa L., formerly called Cimicifuga racemosa (L.) Nutt.] were evaluated for… (More)
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Highly Cited
1999
Highly Cited
1999
We studied whether serotonin release in the CNS is inhibited via cannabinoid receptors. In mouse brain cortex slices preincubated… (More)
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Highly Cited
1994
Highly Cited
1994
Mechanisms underlying the hyperalgesia induced by a single systemic injection of nerve growth factor (NGF) in adult rats were… (More)
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1993
1993
The effects of agonists and antagonists of 5-hydroxytryptamine (5-HT) receptors on the release of endogenous 5-HT from… (More)
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Highly Cited
1993
Highly Cited
1993
An intron-containing gene encoding a novel human serotonin (5-HT) receptor was isolated from human genomic and cDNA libraries… (More)
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1992
1992
1. 8-Hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) dose-dependently induced hypothermia in mice. 2. The 5-HT1A receptor… (More)
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Highly Cited
1989
Highly Cited
1989
The signal transduction pathways of the cloned human 5-HT1A receptor have been examined in two mammalian cell lines transiently… (More)
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Highly Cited
1988
Highly Cited
1988
Rat brain cortex slices preincubated with 3H-serotonin were superfused with physiological salt solution (containing citalopram… (More)
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1988
1988
[3H]ICS 205-930 recognition sites were analyzed in membranes prepared from murine neuroblastoma N1E-115 cells. [3H]ICS 205-930… (More)
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1972
1972
Methiothepin (1-[10,11-dihydro-8-(methylthio)dibenzo[b,f] thiepin-10-yl]-4-methylpiperazine maleate), a representative of a new… (More)
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