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Methiothepin

Known as: Piperazine, 1-(10,11-dihydro-8-(methylthio)dibenzo(b,f)thiepin-10-yl)-4-methyl-, Methiothepin [Chemical/Ingredient], Metitepine 
A serotonin receptor antagonist in the CENTRAL NERVOUS SYSTEM used as an antipsychotic.
National Institutes of Health

Related topics

Related topics

10 relations

Broader (2)

Antipsychotic AgentsSerotonin Antagonists
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Narrower (1)

Methiothepin Maleate

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2000
2000
Clozapine downregulates 5-hydroxytryptamine6 (5-HT6) and upregulates 5-HT7 receptors in HeLa cells
Highly Cited
1998
Highly Cited
1998
Selective labelling of 5-HT7 receptor recognition sites in rat brain using [3H]5-carboxamidotryptamine
Highly Cited
1997
Highly Cited
1997
Differential effects of three 5-HT receptor antagonists on the performance of rats in attentional and working memory tasks
Review
1995
Review
1995
Ventral tegmental area 5-HT receptors: mesolimbic dopamine release and behavioural studies
Highly Cited
1992
Highly Cited
1992
5-Hydroxytryptamine-induced sensitization and activation of peripheral fibres in the neonatal rat are mediated via different 5-hydroxytryptamine-receptors
1992
1992
Serotonergic fibers induce a long-lasting inhibition of monosynaptic reflex in the neonatal rat spinal cord
Highly Cited
1989
Highly Cited
1989
Acetylcholine release from rat hippocampal slices is modulated by 5-hydroxytryptamine.
Highly Cited
1984
Highly Cited
1984
Failure to antagonize the 8-hydroxy-2-di-n-propylamino)tetralin-induced facilitation of male rat sexual behavior by the administration of 5-HT receptor antagonists.
Highly Cited
1982
Highly Cited
1982
The serotonin autoreceptor: Antagonism by quipazine
Highly Cited
1976
Highly Cited
1976
Mechanisms by which quipazine, a putative serotonin receptor agonist, alters brain 5-hydroxyindole metabolism
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