5-Hydroxytryptamine-induced sensitization and activation of peripheral fibres in the neonatal rat are mediated via different 5-hydroxytryptamine-receptors

@article{Rueff19925HydroxytryptamineinducedSA,
  title={5-Hydroxytryptamine-induced sensitization and activation of peripheral fibres in the neonatal rat are mediated via different 5-hydroxytryptamine-receptors},
  author={Alain Rueff and Andy Dray},
  journal={Neuroscience},
  year={1992},
  volume={50},
  pages={899-905}
}
  • A. RueffA. Dray
  • Published 1 October 1992
  • Biology, Chemistry, Computer Science
  • Neuroscience

The different roles of 5-HT(2) and 5-HT(3) receptors on antinociceptive effect of paroxetine in chemical stimuli in mice.

The results indicate that the antinociceptive effect of paroxetine mainly depends on central opioidergic and serotonergic mechanisms, especially by 5-HT(3)-receptor subtypes.

Role of Serotonin Receptors in Inflammatory Pain

Experiments from the laboratory suggest that peripheral activation, by selective subtype receptor agonists, of 5-HT1 receptors induces antinociception and selective antagonists of each receptor dosedependently block this effect.

Mast Cell Degranulation Induces Delayed Rectal Allodynia in Rats: Role of Histamine and 5-HT

Mast cell degranulation initiates a delayed somatic and visceral allodynia, with the participation of serotonin, through5-HT1A receptor activation, on the visceral response.
...

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  • 1960
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