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Definitions of sepsis and septic shock were last revised in 2001. Considerable advances have since been made into the… Expand The worldwide epidemic of obesity has brought considerable attention to research aimed at understanding the biology of adipocytes… Expand The obesity epidemic has forced us to evaluate the role of inflammation in the health complications of obesity. This has led to a… Expand Metabolic disorders including obesity, type 2 diabetes, and atherosclerosis have been viewed historically as lipid storage… Expand The endoplasmic reticulum (ER) is the major site in the cell for protein folding and trafficking and is central to many cellular… Expand Many lines of evidence, including epidemiologic data and extensive clinical and experimental studies, indicate that early life… Expand Diabetes and obesity are two metabolic diseases characterized by insulin resistance and a low-grade inflammation. Seeking an… Expand Metabolic and immune systems are among the most fundamental requirements for survival. Many metabolic and immune response… Expand Nonalcoholic fatty liver disease (NAFLD) has been associated with the insulin‐resistance syndrome, at present defined as the… Expand Metformin is a widely used drug for treatment of type 2 diabetes with no defined cellular mechanism of action. Its glucose… Expand