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Metabolic Biotransformation

Known as: Biotransformation, Biotransformation (Metabolism), biotransformations 
The chemical alteration of an exogenous substance by or in a biological system. The alteration may inactivate the compound or it may result in the… 
National Institutes of Health

Related topics

Related topics

10 relations
BiodegradationBioremediationEnvironmental PollutionMetabolic Detoxication, Drug

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Catabolism

Broader (1)

Metabolism

Papers overview

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Highly Cited
2001
Highly Cited
2001
Plasma Concentrations of Risperidone and 9-Hydroxyrisperidone During Combined Treatment With Paroxetine
The effects of paroxetine on steady-state plasma concentrations of risperidone and its active metabolite 9-hydroxyrisperidone (9… 
Highly Cited
1998
Highly Cited
1998
Directed evolution of an esterase for the stereoselective resolution of a key intermediate in the synthesis of epothilones.
The directed evolution of an esterase from Pseudomonas fluorescens using the mutator strain Epicurian coli XL1-Red was… 
Highly Cited
1992
Highly Cited
1992
Expression of drug-metabolizing enzymes and P-170 glycoprotein in colorectal carcinoma and normal mucosa.
Highly Cited
1986
Highly Cited
1986
Damage to biological tissues induced by radical initiator 2,2'-azobis(2-amidinopropane) dihydrochloride and its inhibition by chain-breaking antioxidants.
Highly Cited
1984
Highly Cited
1984
Novel metabolites of trichloroethylene through dechlorination reactions in rats, mice and humans.
Highly Cited
1983
Highly Cited
1983
Turnover and functions of glutathione studied with isolated hepatic and renal cells.
Suspensions of freshly isolated rat hepatocytes and renal tubular cells contain high levels of reduced glutathione (GSH), which… 
Review
1979
Review
1979
Influence of cigarette smoking on drug metabolism in man.
The pervasiveness of tobacco use in our society and the frequency of altered disposition of many common therapeutic and… 
Highly Cited
1979
Highly Cited
1979
Metabolism of theophylline to caffeine in premature newborn infants.
Highly Cited
1977
Highly Cited
1977
A quantitative assay of mutation induction at the hypoxanthine-guanine phosphoribosyl transferase locus in Chinese hamster ovary cells (CHO/HGPRT system): utilization with a variety of mutagenic…
Highly Cited
1972
Highly Cited
1972
Metabolism of steroid and amino acid moieties of conjugated bile acids in man. I. Cholylglycine.
Cholyl-2,4-(3)H-glycine-1-(14)C was administered orally to eight healthy subjects with indwelling nasoduodenal tubes. The… 
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