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Metabolic Biotransformation

Known as: Biotransformation, Biotransformation (Metabolism), biotransformations 
The chemical alteration of an exogenous substance by or in a biological system. The alteration may inactivate the compound or it may result in the… 
National Institutes of Health

Related topics

Related topics

10 relations
BiodegradationBioremediationEnvironmental PollutionMetabolic Detoxication, Drug

Narrower (1)

Catabolism

Broader (1)

Metabolism

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2013
Review
2013
Cytochrome P450 enzymes in drug metabolism: regulation of gene expression, enzyme activities, and impact of genetic variation.
Review
2008
Review
2008
Cytochrome p450 and chemical toxicology.
  • F. Guengerich
  • Chemical research in toxicology
  • 2008
  • Corpus ID: 17548932
The field of cytochrome P450 (P450) research has developed considerably over the past 20 years, and many important papers on the… 
Review
2007
Review
2007
Enzyme Immobilization: The Quest for Optimum Performance
Immobilization is often the key to optimizing the operational performance of an enzyme in industrial processes, particularly for… 
Review
2007
Review
2007
Review on the toxicity, occurrence, metabolism, detoxification, regulations and intake of zearalenone: an oestrogenic mycotoxin.
Review
2006
Review
2006
Bile salt biotransformations by human intestinal bacteria Published, JLR Papers in Press, November 18, 2005.
Secondary bile acids, produced solely by intestinal bacteria, can accumulate to high levels in the enterohepatic circulation of… 
Highly Cited
2005
Highly Cited
2005
Pharmacogenetics of tamoxifen biotransformation is associated with clinical outcomes of efficacy and hot flashes.
  • M. Goetz, J. Rae, J. Ingle
  • Journal of clinical oncology : official journal…
  • 2005
  • Corpus ID: 41296042
PURPOSE Polymorphisms in tamoxifen metabolizing genes affect the plasma concentration of tamoxifen metabolites, but their effect… 
Review
2003
Review
2003
Fish bioaccumulation and biomarkers in environmental risk assessment: a review.
Review
2002
Review
2002
The clinical importance of the metabolite equol-a clue to the effectiveness of soy and its isoflavones.
Equol [7-hydroxy-3-(4'-hydroxyphenyl)-chroman] is a nonsteroidal estrogen of the isoflavone class. It is exclusively a product of… 
Review
1997
Review
1997
Microbial production of surfactants and their commercial potential
  • J. Desai, I. Banat
  • Microbiology and molecular biology reviews : MMBR
  • 1997
  • Corpus ID: 41445216
Many microorganisms, especially bacteria, produce biosurfactants when grown on water-immiscible substrates. Biosurfactants are… 
Highly Cited
1994
Highly Cited
1994
Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.
Interindividual variations in the level and activity of cytochrome P-450 enzymes were investigated in the liver microsomes of 30… 
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