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Metabolic Biotransformation

Known as: Biotransformation, Biotransformation (Metabolism), biotransformations 
The chemical alteration of an exogenous substance by or in a biological system. The alteration may inactivate the compound or it may result in the… 
National Institutes of Health

Related topics

Related topics

10 relations
BiodegradationBioremediationEnvironmental PollutionMetabolic Detoxication, Drug

Narrower (1)

Catabolism

Broader (1)

Metabolism

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2008
Review
2008
Human exposure to bisphenol A by biomonitoring: methods, results and assessment of environmental exposures.
Review
2004
Review
2004
Apoptosis as a novel target for cancer chemoprevention.
Cancer chemopreventive agents are typically natural products or their synthetic analogs that inhibit the transformation of normal… 
Review
2002
Review
2002
Mechanisms of arsenic biotransformation.
Review
2002
Review
2002
Current perspectives on the clinical experience, pharmacology, and continued development of the camptothecins.
The camptothecins are a maturing class of anticancer agents. In this article, we review the pharmacology and antitumor activity… 
Highly Cited
2002
Highly Cited
2002
The metabolic fate of dietary polyphenols in humans.
Review
2000
Review
2000
Properties and Synthetic Applications of Enzymes in Organic Solvents.
Biotransformations already represent an effective and sometimes preferable alternative to chemical synthesis for the production… 
Review
1998
Review
1998
The mammalian carboxylesterases: from molecules to functions.
Multiple carboxylesterases (EC 3.1.1.1) play an important role in the hydrolytic biotransformation of a vast number of… 
Highly Cited
1997
Highly Cited
1997
Expression of CYP3A in the human liver--evidence that the shift between CYP3A7 and CYP3A4 occurs immediately after birth.
CYP3A isoforms are responsible for the biotransformation of a wide variety of exogenous chemicals and endogenous steroids in… 
Highly Cited
1994
Highly Cited
1994
Human microsomal epoxide hydrolase: genetic polymorphism and functional expression in vitro of amino acid variants.
Human microsomal epoxide hydrolase (mEH) is a biotransformation enzyme that metabolizes reactive epoxide intermediates to more… 
Highly Cited
1981
Highly Cited
1981
Comparison of the urinary excretion of arsenic metabolites after a single oral dose of sodium arsenite, monomethylarsonate, or dimethylarsinate in man
SummaryThe urinary elimination of the metabolites of arsenic has been followed up as a function of time in volunteers who… 
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