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Antioxidant activity applying an improved ABTS radical cation decolorization assay.
A method for the screening of antioxidant activity is reported as a decolorization assay applicable to both lipophilic and hydrophilic antioxidants, including flavonoids, hydroxycinnamates,Expand
Structure-antioxidant activity relationships of flavonoids and phenolic acids.
The factors underlying the influence of the different classes of polyphenols in enhancing their resistance to oxidation are discussed and support the contention that the partition coefficients of the flavonoids as well as their rates of reaction with the relevant radicals define the antioxidant activities in the lipophilic phase. Expand
A novel method for measuring antioxidant capacity and its application to monitoring the antioxidant status in premature neonates.
The method has been applied to investigate the total plasma antioxidant capacity of neonates and how this may be compromised in prematurity, and an antioxidant ranking was established based on their reactivity relative to a 1.0 mmol/l Trolox standard. Expand
Antioxidant properties of phenolic compounds
It is now possible to establish the antioxidant activities of plant-derived flavonoids in the aqueous and lipophilic phases, and to assess the extent to which the total antioxidant potentials of wine and tea can be accounted for by the activities of individual polyphenols. Expand
Total antioxidant status in plasma and body fluids.
The total antioxidant status in plasma and body fluids is discussed, which is based on inhibition of spontaneous tissue autoxidation by antioxidants. Expand
The Antioxidant Activity of Regularly Consumed Fruit and Vegetables Reflects their Phenolic and Vitamin C Composition
Fruit and vegetables rich in anthocyanins demonstrated the highest antioxidant activities, followed by those rich in flavanones and flavonols, while the hydroxycinnamate-rich fruit consistently elicited the lower antioxidant activities. Expand
Functional food science and defence against reactive oxidative species.
The science base that underpins the argument that oxidative damage is a significant causative factor in the development of human diseases and that antioxidants are capable of preventing or ameliorating these disease processes is assessed critically. Expand
Flavonoids: antioxidants or signalling molecules?
A clear understanding of the mechanisms of action of flavonoids, either as antioxidants or modulators of cell signalling, and the influence of their metabolism on these properties are key to the evaluation of these potent biomolecules as anticancer agents, cardioprotectants, and inhibitors of neurodegeneration. Expand
Factors influencing the antioxidant activity determined by the ABTS.+ radical cation assay.
This study introduces a simple direct antioxidant assay, based on the reduction of the ABTS, and compares it with the myoglobin/ABTS, establishing that the antioxidants studied to date in the latter assay act by scavenging the AB TS. Expand
Flavonoid permeability across an in situ model of the blood-brain barrier.
The results demonstrate that flavonoids are able to traverse the blood-brain barrier in vivo, however, the permeability of certain flavonoid in vivo is influenced by their lipophilicity and interactions with efflux transporters. Expand