FAQ

Matrix Metalloproteinase 16

Known as: Membrane Type 3 Matrix Metalloproteinase, Membrane-Type-3 Matrix Metalloproteinase, Metalloproteinase, MMP16 
A transmembrane domain-containing matrix metalloproteinase. It is synthesized as an inactive zymogen that is activated by the proteolytic action of… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1997-2018
0519972018

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10 relations
In BloodMMP16 geneProcess of secretionadministration & dosage
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MMP16 protein, human

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Matrix Metalloproteinase 16
physiological aspects
chemical synthesis
standards characteristics
Process of secretion
MMP16 gene

Papers overview

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Highly Cited
2004
Highly Cited
2004
Differential inhibition of membrane type 3 (MT3)-matrix metalloproteinase (MMP) and MT1-MMP by tissue inhibitor of metalloproteinase (TIMP)-2 and TIMP-3 rgulates pro-MMP-2 activation.
The membrane type (MT)-matrix metalloproteinases (MMPs) constitute a subgroup of membrane-anchored MMPs that are major mediators… (More)
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2004
2004
The low density lipoprotein receptor-related protein LRP is regulated by membrane type-1 matrix metalloproteinase (MT1-MMP) proteolysis in malignant cells.
We demonstrate that the presentation of LRP and the subsequent uptake of its ligands by malignant cells are both strongly… (More)
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Highly Cited
2003
Highly Cited
2003
Cleavage of syndecan-1 by membrane type matrix metalloproteinase-1 stimulates cell migration.
The transmembrane heparan sulfate proteoglycan syndecan-1 was identified from a human placenta cDNA library by the expression… (More)
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Highly Cited
2002
Highly Cited
2002
Endothelial tubulogenesis within fibrin gels specifically requires the activity of membrane-type-matrix metalloproteinases (MT-MMPs).
Macro- and microvascular endothelial cells (EC) formed tubular structures when cultured within a 3D fibrin matrix, a process that… (More)
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Highly Cited
2002
Highly Cited
2002
Increased expression of membrane type 3-matrix metalloproteinase in human atherosclerotic plaque: role of activated macrophages and inflammatory cytokines.
BACKGROUND Matrix metalloproteinases (MMPs) are thought to play a prominent role in atherogenesis and destabilization of plaque… (More)
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Highly Cited
2001
Highly Cited
2001
Matrix-dependent proteolysis of surface transglutaminase by membrane-type metalloproteinase regulates cancer cell adhesion and locomotion.
Cell invasion requires cooperation between adhesion receptors and matrix metalloproteinases (MMPs). Membrane type (MT)-MMPs have… (More)
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Highly Cited
2000
Highly Cited
2000
Role of MT-MMPs and MMP-2 in pancreatic cancer progression.
Activation of matrix metalloproteinase-2 (MMP-2) by the membrane-type matrix metalloproteinases (MT-MMPs) has been associated… (More)
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2000
2000
Role for activation of matrix metalloproteinases in the pathogenesis of pulmonary lymphangioleiomyomatosis.
BACKGROUND Matrix metalloproteinases (MMPs) have been shown to be involved in the pathogenesis of the destructive pulmonary… (More)
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Highly Cited
1999
Highly Cited
1999
Expression and tissue localization of membrane-type 1, 2, and 3 matrix metalloproteinases in human astrocytic tumors.
Three different membrane-type matrix metalloproteinases (MT1-, MT2-, and MT3-MMPs) are known to activate in vitro the zymogen of… (More)
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1997
1997
Expression of three membrane-type matrix metalloproteinases (MT-MMPs) in rat vascular smooth muscle cells and characterization of MT3-MMPs with and without transmembrane domain.
Matrix metalloproteinases (MMPs) produced by rat smooth muscle cells (SMCs) were investigated. SMCs expressed three kinds of… (More)
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