Matrix Metalloproteinase 15

Known as: Membrane Type 2 Matrix Metalloproteinase, Membrane-Type-2 Matrix Metalloproteinase, Metalloproteinase, MMP15 
A transmembrane domain-containing matrix metalloproteinase that plays a role in the cleavage of proteins in the pericellular environment. It is… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1980-2017
051019802017

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7 relations
In BloodMMP15 geneProcess of secretionaspects of radiation effects
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Related mentions per year

Related mentions per year

1936-2019
19401960198020002020
Matrix Metalloproteinase 15
standards characteristics
physiological aspects
chemical synthesis
MMP15 gene
In Blood

Papers overview

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Highly Cited
2002
Highly Cited
2002
Matrix Metalloproteinases (MMPs) Regulate Fibrin-invasive Activity via MT1-MMP–dependent and –independent Processes
Cross-linked fibrin is deposited in tissues surrounding wounds, inflammatory sites, or tumors and serves not only as a supporting… (More)
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Highly Cited
2002
Highly Cited
2002
Endothelial tubulogenesis within fibrin gels specifically requires the activity of membrane-type-matrix metalloproteinases (MT-MMPs).
Macro- and microvascular endothelial cells (EC) formed tubular structures when cultured within a 3D fibrin matrix, a process that… (More)
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Highly Cited
2001
Highly Cited
2001
Matrix-dependent proteolysis of surface transglutaminase by membrane-type metalloproteinase regulates cancer cell adhesion and locomotion.
Cell invasion requires cooperation between adhesion receptors and matrix metalloproteinases (MMPs). Membrane type (MT)-MMPs have… (More)
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Highly Cited
2000
Highly Cited
2000
Regulation of Cell Invasion and Morphogenesis in a Three-Dimensional Type I Collagen Matrix by Membrane-Type Matrix Metalloproteinases 1, 2, and 3
During tissue-invasive events, migrating cells penetrate type I collagen-rich interstitial tissues by mobilizing undefined… (More)
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Highly Cited
2000
Highly Cited
2000
Glioma cell extracellular matrix metalloproteinase inducer (EMMPRIN) (CD147) stimulates production of membrane-type matrix metalloproteinases and activated gelatinase A in co-cultures with brain…
Extracellular matrix metalloproteinase inducer (EMMPRIN) also called CD147, basigin or M6 in the human is a member of the… (More)
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Highly Cited
2000
Highly Cited
2000
Role of MT-MMPs and MMP-2 in pancreatic cancer progression.
Activation of matrix metalloproteinase-2 (MMP-2) by the membrane-type matrix metalloproteinases (MT-MMPs) has been associated… (More)
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Highly Cited
1999
Highly Cited
1999
Expression and tissue localization of membrane-type 1, 2, and 3 matrix metalloproteinases in human astrocytic tumors.
Three different membrane-type matrix metalloproteinases (MT1-, MT2-, and MT3-MMPs) are known to activate in vitro the zymogen of… (More)
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Highly Cited
1997
Highly Cited
1997
Membrane-type matrix metalloproteinases 1 and 2 exhibit broad-spectrum proteolytic capacities comparable to many matrix metalloproteinases.
Soluble proenzyme forms of the catalytic domains of membrane-type matrix metalloproteinases 1 and 2 (MT1-MMP and MT2-MMP) and a… (More)
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Highly Cited
1997
Highly Cited
1997
Expression and tissue localization of membrane-types 1, 2, and 3 matrix metalloproteinases in human invasive breast carcinomas.
Activation of the zymogen of matrix metalloproteinase 2 (proMMP-2, progelatinase A) possibly is one of the key steps in invasion… (More)
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Highly Cited
1997
Highly Cited
1997
Implication of collagen type I-induced membrane-type 1-matrix metalloproteinase expression and matrix metalloproteinase-2 activation in the metastatic progression of breast carcinoma.
We have previously demonstrated that fibroblasts and invasive human breast carcinoma (HBC) cells specifically activate matrix… (More)
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