Enhanced expression of membrane type-1 matrix metalloproteinase in mesangial proliferative glomerulonephritis.

@article{Hayashi1998EnhancedEO,
  title={Enhanced expression of membrane type-1 matrix metalloproteinase in mesangial proliferative glomerulonephritis.},
  author={Koichi Hayashi and Shiwori Osada and Ken-ichi Shofuda and Satoshi Horikoshi and Isao Shirato and Yasuhiko Tomino},
  journal={Journal of the American Society of Nephrology : JASN},
  year={1998},
  volume={9 12},
  pages={2262-71}
}
Matrix metalloproteinase-2 (MMP-2, gelatinase A) is involved in the inflammatory and sclerotic events of glomerular diseases. Newly identified membrane-type matrix metalloproteinases (MT-MMP) have been shown to activate specifically proMMP-2. To date, several types of MT-MMP have been cloned; however, their expressions in glomerular diseases have not been evaluated. To investigate the role of MT-MMP in glomerular diseases, the glomerular gene expression and enzymatic activity of MT-MMP were… CONTINUE READING
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Cell-cell contact down-regubates expression of membrane type metabboproteinase- 1 (MT1 MMP) in a mouse mammary gland epithebial cell line

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