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Major Histocompatibility Complex

Known as: Complices, Major Histocompatibility, major histocompatibility complex (MHC), Complex, Histocompatibility 
The genetic region which contains the loci of genes which determine the structure of the serologically defined (SD) and lymphocyte-defined (LD… 
National Institutes of Health

Related topics

Related topics

8 relations
Genes, MHC Class IHLA ComplexHistocompatibility Antigens Class IHistocompatibility Antigens Class II

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
Licensing of natural killer cells by host major histocompatibility complex class I molecules
Self versus non-self discrimination is a central theme in biology from plants to vertebrates, and is particularly relevant for… 
Review
1999
Review
1999
Immunodominance in major histocompatibility complex class I-restricted T lymphocyte responses.
Of the many thousands of peptides encoded by a complex foreign antigen that can potentially be presented to CD8+ T cells (TCD8… 
Highly Cited
1997
Highly Cited
1997
A Common Inhibitory Receptor for Major Histocompatibility Complex Class I Molecules on Human Lymphoid and Myelomonocytic Cells
Natural killer (NK) cell–mediated lysis is negatively regulated by killer cell inhibitory receptors specific for major… 
Highly Cited
1996
Highly Cited
1996
Cell stress-regulated human major histocompatibility complex class I gene expressed in gastrointestinal epithelium.
Conventional major histocompatibility complex (MHC) class I genes encode molecules that present intracellular peptide antigens to… 
Highly Cited
1996
Highly Cited
1996
Influence of combinations of human major histocompatibility complex genes on the course of HIV–1 infection
Major histocompatibility complex (MHC) genes (HLA in humans) regulate the immune response to foreign antigens. Molecular and… 
Highly Cited
1996
Highly Cited
1996
Phenotypic Analysis of Antigen-Specific T Lymphocytes
Identification and characterization of antigen-specific T lymphocytes during the course of an immune response is tedious and… 
Highly Cited
1991
Highly Cited
1991
Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major…
Interleukin 10 (IL-10) and viral IL-10 (v-IL-10) strongly reduced antigen-specific proliferation of human T cells and CD4+ T cell… 
Highly Cited
1989
Highly Cited
1989
Site-directed mutagenesis by overlap extension using the polymerase chain reaction.
Highly Cited
1988
Highly Cited
1988
Pattern of nucleotide substitution at major histocompatibility complex class I loci reveals overdominant selection
The major histocompatibility complex (MHC) loci are known to be highly polymorphic in humans, mice and certain other mammals… 
Highly Cited
1987
Highly Cited
1987
The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens
Most of the polymorphic amino acids of the class I histocompatibility antigen, HLA-A2, are clustered on top of the molecule in a… 
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