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Major Histocompatibility Complex
Known as:
Complices, Major Histocompatibility
, major histocompatibility complex (MHC)
, Complex, Histocompatibility
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The genetic region which contains the loci of genes which determine the structure of the serologically defined (SD) and lymphocyte-defined (LD…
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National Institutes of Health
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Related topics
Related topics
8 relations
Genes, MHC Class I
HLA Complex
Histocompatibility Antigens Class I
Histocompatibility Antigens Class II
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
Licensing of natural killer cells by host major histocompatibility complex class I molecules
Sungjin Kim
,
J. Poursine‐Laurent
,
+8 authors
W. Yokoyama
Nature
2005
Corpus ID: 4360255
Self versus non-self discrimination is a central theme in biology from plants to vertebrates, and is particularly relevant for…
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Review
1999
Review
1999
Immunodominance in major histocompatibility complex class I-restricted T lymphocyte responses.
J. Yewdell
,
J. Bennink
Annual Review of Immunology
1999
Corpus ID: 34186844
Of the many thousands of peptides encoded by a complex foreign antigen that can potentially be presented to CD8+ T cells (TCD8…
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Highly Cited
1997
Highly Cited
1997
A Common Inhibitory Receptor for Major Histocompatibility Complex Class I Molecules on Human Lymphoid and Myelomonocytic Cells
M. Colonna
,
F. Navarro
,
+6 authors
M. López-Botet
Journal of Experimental Medicine
1997
Corpus ID: 6299724
Natural killer (NK) cell–mediated lysis is negatively regulated by killer cell inhibitory receptors specific for major…
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Highly Cited
1996
Highly Cited
1996
Cell stress-regulated human major histocompatibility complex class I gene expressed in gastrointestinal epithelium.
V. Groh
,
S. Bahram
,
S. Bauer
,
A. Herman
,
M. Beauchamp
,
T. Spies
Proceedings of the National Academy of Sciences…
1996
Corpus ID: 34786099
Conventional major histocompatibility complex (MHC) class I genes encode molecules that present intracellular peptide antigens to…
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Highly Cited
1996
Highly Cited
1996
Influence of combinations of human major histocompatibility complex genes on the course of HIV–1 infection
R. Kaslow
,
M. Carrington
,
+12 authors
D. Mann
Nature Network Boston
1996
Corpus ID: 9621499
Major histocompatibility complex (MHC) genes (HLA in humans) regulate the immune response to foreign antigens. Molecular and…
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Highly Cited
1996
Highly Cited
1996
Phenotypic Analysis of Antigen-Specific T Lymphocytes
J. Altman
,
P. Moss
,
+5 authors
Mark M. Davis
Science
1996
Corpus ID: 12667633
Identification and characterization of antigen-specific T lymphocytes during the course of an immune response is tedious and…
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Highly Cited
1991
Highly Cited
1991
Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major…
R. de Waal Malefyt
,
J. Haanen
,
+7 authors
J. D. de Vries
Journal of Experimental Medicine
1991
Corpus ID: 3017363
Interleukin 10 (IL-10) and viral IL-10 (v-IL-10) strongly reduced antigen-specific proliferation of human T cells and CD4+ T cell…
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Highly Cited
1989
Highly Cited
1989
Site-directed mutagenesis by overlap extension using the polymerase chain reaction.
S. Ho
,
H. Hunt
,
R. Horton
,
J. K. Pullen
,
L. Pease
Gene
1989
Corpus ID: 410626
Highly Cited
1988
Highly Cited
1988
Pattern of nucleotide substitution at major histocompatibility complex class I loci reveals overdominant selection
A. Hughes
,
M. Nei
Nature
1988
Corpus ID: 4352981
The major histocompatibility complex (MHC) loci are known to be highly polymorphic in humans, mice and certain other mammals…
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Highly Cited
1987
Highly Cited
1987
The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens
P. Bjorkman
,
M. Saper
,
B. Samraoui
,
W. Bennett
,
J. Strominger
,
D. Wiley
Nature
1987
Corpus ID: 19220084
Most of the polymorphic amino acids of the class I histocompatibility antigen, HLA-A2, are clustered on top of the molecule in a…
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