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Major Histocompatibility Complex

Known as: Complices, Major Histocompatibility, major histocompatibility complex (MHC), Complex, Histocompatibility 
The genetic region which contains the loci of genes which determine the structure of the serologically defined (SD) and lymphocyte-defined (LD… Expand
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
Self versus non-self discrimination is a central theme in biology from plants to vertebrates, and is particularly relevant for… Expand
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Review
1999
Review
1999
Of the many thousands of peptides encoded by a complex foreign antigen that can potentially be presented to CD8+ T cells (TCD8… Expand
Highly Cited
1997
Highly Cited
1997
Natural killer (NK) cell–mediated lysis is negatively regulated by killer cell inhibitory receptors specific for major… Expand
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Highly Cited
1996
Highly Cited
1996
Conventional major histocompatibility complex (MHC) class I genes encode molecules that present intracellular peptide antigens to… Expand
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Highly Cited
1996
Highly Cited
1996
Major histocompatibility complex (MHC) genes (HLA in humans) regulate the immune response to foreign antigens. Molecular and… Expand
Highly Cited
1996
Highly Cited
1996
Identification and characterization of antigen-specific T lymphocytes during the course of an immune response is tedious and… Expand
Highly Cited
1991
Highly Cited
1991
Interleukin 10 (IL-10) and viral IL-10 (v-IL-10) strongly reduced antigen-specific proliferation of human T cells and CD4+ T cell… Expand
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Highly Cited
1989
Highly Cited
1989
  • A. Hughes, M. Nei
  • Proceedings of the National Academy of Sciences…
  • 1989
  • Corpus ID: 25810130
To study the mechanism of maintenance of polymorphism at major histocompatibility complex (MHC) loci, synonymous and… Expand
Highly Cited
1988
Highly Cited
1988
The major histocompatibility complex (MHC) loci are known to be highly polymorphic in humans, mice and certain other mammals… Expand
Highly Cited
1987
Highly Cited
1987
Most of the polymorphic amino acids of the class I histocompatibility antigen, HLA-A2, are clustered on top of the molecule in a… Expand