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Major Histocompatibility Complex
Known as:
Complices, Major Histocompatibility
, major histocompatibility complex (MHC)
, Complex, Histocompatibility
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The genetic region which contains the loci of genes which determine the structure of the serologically defined (SD) and lymphocyte-defined (LD…
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National Institutes of Health
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Related topics
Related topics
8 relations
Genes, MHC Class I
HLA Complex
Histocompatibility Antigens Class I
Histocompatibility Antigens Class II
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
1997
Review
1997
Evolving views of the major histocompatibility complex.
J. Gruen
,
S. Weissman
Blood
1997
Corpus ID: 14223720
THE MAJOR HISTOCOMPATIBILITY complex (MHC) is an extended cluster of genes that are remarkable for the number and importance of…
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Highly Cited
1997
Highly Cited
1997
Early endosomes and a late endocytic compartment generate different peptide-class II MHC complexes via distinct processing mechanisms.
J. Griffin
,
R. Chu
,
C. Harding
Journal of Immunology
1997
Corpus ID: 5718629
Class II MHC Ag-processing compartments and mechanisms were compared for four antigenic epitopes from hen egg lysozyme (HEL) and…
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Highly Cited
1992
Highly Cited
1992
Peptide-induced conformational changes in class I heavy chains alter major histocompatibility complex recognition
J. Bluestone
,
S. Jameson
,
Stephen Miller
,
R. Dick
Journal of Experimental Medicine
1992
Corpus ID: 2828880
Small peptides, derived from endogenous proteins bind within the antigen binding groove created by the beta-pleated sheets and…
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Highly Cited
1989
Highly Cited
1989
Binding of staphylococcal enterotoxin A to HLA-DR on B cell lines.
Hans Fischer
,
M. Dohlsten
,
M. Lindvall
,
Hans-Olov Sjögren
,
Roland Carlsson
Journal of Immunology
1989
Corpus ID: 28563031
Staphylococcal enterotoxin A (SEA) is a potent polyclonal T cell activator. Its activating effect is entirely dependent upon its…
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Highly Cited
1988
Highly Cited
1988
Lymphocytes isolated from the intestinal lamina propria of normal nonhuman primates have increased expression of genes associated with T-cell activation.
Martin Zeitz
,
W. C. Greene
,
N. Peffer
,
Stephen P. James
Gastroenterology
1988
Corpus ID: 25042594
Highly Cited
1981
Highly Cited
1981
A pseudogene homologous to mouse transplantation antigens: Transplantation antigens are encoded by eight exons that correlate with protein domains
M. Steinmetz
,
K. Moore
,
+4 authors
L. Hood
Cell
1981
Corpus ID: 36049354
Review
1981
Review
1981
Primary structural: analysis of the transplantation antigens of the murine H-2 major histocompatibility complex.
S. Nathenson
,
H. Uehara
,
B. Ewenstein
,
T. Kindt
,
J. Coligan
Annual Review of Biochemistry
1981
Corpus ID: 29998654
PERSPECI1VES AND SUMMARY 1026 INTRODUCfION 1027 DETERMINATION OF PRIMARY STRUcruRE BY RADIOCHEMICAL METHODOLOGY 1029 General…
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Highly Cited
1977
Highly Cited
1977
Antigen presentation in the murine T-lymphocyte proliferative response. I. Requirement for genetic identity at the major histocompatibility complex
A. Yano
,
R. Schwartz
,
W. Paul
Journal of Experimental Medicine
1977
Corpus ID: 9430017
A method is described for stimulating proliferation in primed populations of murine T lymphocytes using antigen bound to…
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Highly Cited
1974
Highly Cited
1974
Linkage of HL‐A and GBG 1
Fred H. Allen
Vox Sanguinis
1974
Corpus ID: 5277297
Abstract. The HL‐A histocompatibility locus is closely linked to that for the glycinerich β‐glycoprotein polymorphism. No…
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Highly Cited
1972
Highly Cited
1972
SEROLOGICALLY DEFINED AND LYMPHOCYTE-DEFINED COMPONENTS OF THE MAJOR HISTOCOMPATIBILITY COMPLEX IN THE MOUSE
F. Bach
,
M. Widmer
,
M. Bach
,
J. Klein
Journal of Experimental Medicine
1972
Corpus ID: 7971433
The mixed leukocyte culture (MLC) test is an in vitro model of the recognition phase of the homograft response. For the most part…
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