Histocompatibility Antigens Class I

Known as: Human Leukocyte Antigen, Major Histocompatibility Complex Class 1, Class I Histocompatibility Antigens 
Membrane glycoproteins consisting of an alpha subunit and a BETA 2-MICROGLOBULIN beta subunit. In humans, highly polymorphic genes on CHROMOSOME 6… (More)
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
CTX-M β-lactamases are considered a paradigm in the evolution of a resistance mechanism. Incorporation of different chromosomal… (More)
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Highly Cited
2010
Highly Cited
2010
MHC class I plays a critical role in the immune defense against viruses and tumors by presenting antigens to CD8 T cells. An NLR… (More)
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Highly Cited
2009
Highly Cited
2009
A Swedish patient of Indian origin traveled to New Delhi, India, and acquired a urinary tract infection caused by a carbapenem… (More)
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Highly Cited
2007
Highly Cited
2007
OBJECTIVE Variation in the major histocompatibility complex (MHC) on chromosome 6p21 is known to influence susceptibility to… (More)
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Review
2002
Review
2002
Class switch recombination (CSR) and somatic hypermutation (SHM) have been considered to be mediated by different molecular… (More)
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Highly Cited
1998
Highly Cited
1998
The class II transactivator (CIITA) is a key regulatory factor that controls expression of the major histocompatibility complex… (More)
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Highly Cited
1996
Highly Cited
1996
Conventional major histocompatibility complex (MHC) class I genes encode molecules that present intracellular peptide antigens to… (More)
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Highly Cited
1996
Highly Cited
1996
CIITA activates the expression of multiple genes involved in antigen presentation and it is believed to be required for both… (More)
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Highly Cited
1995
Highly Cited
1995
CIITA (a major histocompatibility complex [MHC] class II transactivator) has been shown to be required for the expression of MHC… (More)
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Highly Cited
1990
Highly Cited
1990
PRESENTATION of an exogenous protein antigen to helper (CD4+) T-lymphocytes by antigen presenting cells (APC) generally requires… (More)
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