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Genes, MHC Class I

Known as: Gene, Class I, Class I Genes, MHC Class I Genes 
Genetic loci in the vertebrate major histocompatibility complex which encode polymorphic characteristics not related to immune responsiveness or… 
National Institutes of Health

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Related topics

21 relations
Antigen PresentationHLA Class I Histocompatibility Antigen, A-0301 Alpha ChainHLA Class I Histocompatibility Antigen, A-1 Alpha ChainHLA Class I Histocompatibility Antigen, A-11 alpha Chain

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Genes, H-2 Class I

Papers overview

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2016
2016
Vanilloid Receptor 1 Agonists, Capsaicin and Resiniferatoxin, Enhance MHC Class I-restricted Viral Antigen Presentation in Virus-infected Dendritic Cells
DCs, like the sensory neurons, express vanilloid receptor 1 (VR1). Here we demonstrate that the VR1 agonists, capsaicin (CP) and… 
2014
2014
Improved pan-specific MHC class I peptide-binding predictions using a novel representation of the MHC-binding cleft environment.
Major histocompatibility complex (MHC) molecules play a key role in cell-mediated immune responses presenting bounded peptides… 
2011
2011
Self MHC class I-licensed NK cells enhance adaptive CD8 T-cell viral immunity.
MHC class I (MHC I) is essential to NK- and T-cell effector and surveillance functions. However, it is unknown whether MHC I… 
2010
2010
MHC screening for marsupial conservation: extremely low levels of class II diversity indicate population vulnerability for an endangered Australian marsupial
Variation at genetic regions of functional significance is a new focus in conservation genetics. One of the prime candidates for… 
2008
2008
Modulation of graft arteriosclerosis in a rat carotid transplantation model.
Review
2007
Review
2007
Tolerogenic property of MHC class I and class II molecules: lessons from a gene therapy approach.
Conditions allowing the development of a stable state of hematopoietic chimerism, i.e., the coexistence of foreign and recipient… 
2005
2005
The H-2Kk MHC Peptide-Binding Groove Anchors the Backbone of an Octameric Antigenic Peptide in an Unprecedented Mode12
A wealth of data has accumulated on the structure of mouse MHC class I (MHCI) molecules encoded by the H-2b and H-2d haplotypes… 
2003
2003
Stalk region of beta-chain enhances the coreceptor function of CD8.
CD8 glycoproteins are expressed as either alphaalpha homodimers or alphabeta heterodimers on the surface of T cells. CD8alphabeta… 
2002
2002
Generation of CD3+CD8low Thymocytes in the HIV Type 1-Infected Thymus1
Infection with the HIV type 1 (HIV-1) can result both in depletion of CD4+ T cells and in the generation of dysfunctional CD8+ T… 
1999
1999
Induction of MHC class I expression on immature thymocytes in HIV-1-infected SCID-hu Thy/Liv mice: evidence of indirect mechanisms.
The SCID-hu Thy/Liv mouse and human fetal thymic organ culture (HF-TOC) models have been used to explore the pathophysiologic… 
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