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Major Groove
One of the two types of grooves found in a right-handed double helix, running between the sugar phosphate backbones of each strand.
National Institutes of Health
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Papers overview
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2017
2017
Characterization of cis‐elements and trans-factors that are involved in RNAi-mediated genome defense in Drosophila melanogaster
S. Kunzelmann
2017
Corpus ID: 91802133
2014
2014
Polymerase Synthesis of DNAs Bearing Vinyl Groups in the Major Groove and their Cleavage by Restriction Endonucleases
M. Mačková
,
R. Pohl
,
Michal Hocek
ChemBioChem
2014
Corpus ID: 205558805
DNA molecules containing 5‐vinyluracil, 5‐vinylcytosine, or 7‐deaza‐7‐vinyladenine were prepared by polymerase incorporation of…
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2011
2011
Synthesis of acetylene linked double-nucleobase nucleos(t)ide building blocks and polymerase construction of DNA containing cytosines in the major groove.
Pavel Kielkowski
,
R. Pohl
,
Michal Hocek
Journal of Organic Chemistry
2011
Corpus ID: 33916165
(Cytosin-5-yl)ethynyl derivatives of pyrimidine and 7-deazaadenine 2-deoxyribonucleosides and nucleoside triphosphates (dNTPs…
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2011
2011
DNA complexes: Durable binders.
Adam R Urbach
Nature Chemistry
2011
Corpus ID: 31773575
A tetra-intercalator compound that threads through a DNA double-helix to form a remarkably stable complex exhibits an unusual…
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2004
2004
Allosteric inhibition of zinc-finger binding in the major groove of DNA by minor-groove binding ligands.
Doan H. Nguyen-Hackley
,
E. Ramm
,
Christina M. Taylor
,
J. Joung
,
P. Dervan
,
C. Pabo
Biochemistry
2004
Corpus ID: 1389128
In recent years, two methods have been developed that may eventually allow the targeted regulation of a broad repertoire of genes…
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1986
1986
Oligonucleotide duplexes containing inosine, 7-deazainosine, tubercidin, nebularine and 7-deazanebularine as substrates for restriction endonucleases HindII, SalI and TaqI.
J. Jiricny
,
S. G. Wood
,
D. Martin
,
A. Ubasawa
Nucleic Acids Research
1986
Corpus ID: 36927586
Synthetic hexadecanucleotide duplexes containing a single purine nucleotide analogue in the recognition sites of the restriction…
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1985
1985
Mode of reversible binding of neocarzinostatin chromophore to DNA: evidence for binding via the minor groove.
D. Dasgupta
,
I. Goldberg
Biochemistry
1985
Corpus ID: 7764097
Two general approaches have been taken to understand the mechanism of the reversible binding of the nonprotein chromophore of…
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1985
1985
A comparison of the structural requirements for DNA cleavage by the isoschizomers HaeIII, BspRI and BsuRI.
H. Wolfes
,
A. Fliess
,
A. Pingoud
European Journal of Biochemistry
1985
Corpus ID: 25724148
We have investigated the structural requirements for DNA cleavage by the isoschizomers HaeIII, BspRI and BsuRI which recognize…
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1976
1976
Recognition of polynucleotides by antibodies to poly(I), poly(C).
M. Guigues
,
M. Leng
Nucleic Acids Research
1976
Corpus ID: 27606143
The binding of anti poly(I). poly (C) Fab fragments to double or triple stranded polynucletides has been studied by fluorescence…
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1974
1974
Localization of chromatin proteins within DNA grooves by methylation of chromatin with dimethyl sulphate
A. Mirzabekov
,
A. F. Melnikova
Molecular Biology Reports
1974
Corpus ID: 21514893
The use of the comparative modification with 3H-dimethyl sulphate (DMS) of free DNA and DNA in different complexes is proposed to…
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