Major Groove

One of the two types of grooves found in a right-handed double helix, running between the sugar phosphate backbones of each strand.
National Institutes of Health

Topic mentions per year

Topic mentions per year

2001-2018
012320012018

Papers overview

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2014
2014
Nitrosourea therapeutics occupies a definite place in cancer therapy but its exact mechanism of action has yet to be established… (More)
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2014
2014
1,3-Butadiene (BD) is an environmental and occupational toxicant classified as a human carcinogen. It is oxidized by cytochrome… (More)
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2013
2013
A cationic 7-aminomethyl-7-deaza-2′-deoxyguanosine (7amG) was incorporated site-specifically into the selfcomplementary duplex d… (More)
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2012
2012
This study investigates the effect of Mg(2+) bound to the DNA major groove on DNA structure and dynamics. The analysis of a… (More)
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2011
2011
As part of an ongoing effort to explore the effect of major groove electrostatics on the thermodynamic stability and structure of… (More)
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2010
2010
DNA polymerase nu (POLN or pol nu) is a newly discovered A family polymerase that generates a high error rate when incorporating… (More)
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2006
2006
Three aromatic disulfides and their two selected congeners were studied in order to see if they could be initiators or catalysts… (More)
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2003
2003
The 3D structural data for a number of protein–DNA complexes were used to analyze the regions of specific contact with the major… (More)
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2003
2003
Suppressor of zeste 12, a Polycomb group gene in Drosophila melanogaster; one piece in the epigenetic puzzle Anna Birve… (More)
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Review
2001
Review
2001
Nucleic acids and proteins are two of the most important biomolecules in any living organism, with the former carrying genetic… (More)
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