Minor groove-binding architectural proteins: structure, function, and DNA recognition.

@article{Bewley1998MinorGA,
  title={Minor groove-binding architectural proteins: structure, function, and DNA recognition.},
  author={Carole A Bewley and Angela M. Gronenborn and G Marius Clore},
  journal={Annual review of biophysics and biomolecular structure},
  year={1998},
  volume={27},
  pages={
          105-31
        }
}
To date, high-resolution structures have been solved for five different architectural proteins complexed to their DNA target sites. These include TATA-box-binding protein, integration host factor (IHF), high mobility group I(Y)[HMG I(Y)], and the HMG-box-containing proteins SRY and LEF-1. Each of these proteins interacts with DNA exclusively through minor groove contacts and alters DNA conformation. This paper reviews the structural features of these complexes and the roles they play in… CONTINUE READING
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References

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Principles of Nucleic Acid Structure, ed

W. Saenger
CR Cantor. New York: Springer-Verlag • 1983
View 9 Excerpts
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Making DNA do a U-turn: IHF and related proteins.

Current opinion in structural biology • 1997
View 1 Excerpt