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Macrophage Scavenger Receptor Types I and II

Known as: Scavenger Receptor Class A, Member 1, Scavenger Receptor Class A Member 1, Macrophage Scavenger Receptor 
Macrophage scavenger receptor types I and II (451 aa, ~50 kDa) is encoded by the human MSR1 gene. This protein plays a role in cholesterol and… 
National Institutes of Health

Related topics

Related topics

13 relations
Cholesterol HomeostasisEarly endosomeIntegral Membrane ProteinsLigand Binding

Broader (1)

Scavenger Receptors, Macrophage

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Structure-activity relations of nanolipoblockers with the atherogenic domain of human macrophage scavenger receptor A.
Oxidized low density lipoprotein (oxLDL) uptake by macrophages is mediated by scavenger receptors and leads to unregulated… 
2006
2006
Development of contrast agents targeted to macrophage scavenger receptors for MRI of vascular inflammation.
Atherosclerosis is a leading cause of death in the U.S. Because there is a potential to prevent coronary and arterial disease… 
Highly Cited
2004
Highly Cited
2004
The Class A Macrophage Scavenger Receptor Attenuates CXC Chemokine Production and the Early Infiltration of Neutrophils in Sterile Peritonitis1
The macrophage scavenger receptor (SR-A) is a multifunctional receptor that is associated with several important pathological… 
2004
2004
Malondialdehyde-acetaldehyde haptenated protein binds macrophage scavenger receptor(s) and induces lysosomal damage.
2003
2003
Adenovirus-mediated gene transfer of a secreted decoy human macrophage scavenger receptor (SR-AI) in LDL receptor knock-out mice.
2000
2000
Adenovirus-mediated gene transfer of a secreted form of human macrophage scavenger receptor inhibits modified low-density lipoprotein degradation and foam-cell formation in macrophages.
BACKGROUND Macrophage scavenger receptors (MSRs) play an important role in the pathogenesis of atherosclerosis. Therefore, local… 
1999
1999
Macrophage specific overexpression of the human macrophage scavenger receptor in transgenic mice, using a 180-kb yeast artificial chromosome, leads to enhanced foam cell formation of isolated…
1999
1999
Role of the buried glutamate in the alpha-helical coiled coil domain of the macrophage scavenger receptor.
The macrophage scavenger receptor exhibits a pH-dependent conformational change around the carboxy-terminal half of the alpha… 
Highly Cited
1998
Highly Cited
1998
Insulin Enhances Macrophage Scavenger Receptor-mediated Endocytic Uptake of Advanced Glycation End Products*
Hyperglycemia accelerates the formation and accumulation of advanced glycation end products (AGE) in plasma and tissue, which may… 
1995
1995
High Endothelial Cells of Postcapillary Venules Express the Scavenger Receptor in Human Peripheral Lymph Nodes
The macrophage scavenger receptor (MSR) is a multipotent receptor that mediates uptake of macromolecules with clustered negative… 
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