Macrophage Scavenger Receptor Types I and II

Known as: Scavenger Receptor Class A, Member 1, Scavenger Receptor Class A Member 1, Macrophage Scavenger Receptor 
Macrophage scavenger receptor types I and II (451 aa, ~50 kDa) is encoded by the human MSR1 gene. This protein plays a role in cholesterol and… (More)
National Institutes of Health

Related topics

Related topics

13 relations
Cholesterol HomeostasisEarly endosomeIntegral Membrane ProteinsLigand Binding
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Broader (1)

Scavenger Receptors, Macrophage

Papers overview

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Highly Cited
2006
Highly Cited
2006
The macrophage scavenger receptor SR-AI/II and lung defense against pneumococci and particles.
The class A macrophage scavenger receptor SR-AI/II is implicated as a pattern recognition receptor for innate immunity, but its… (More)
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Review
2005
Review
2005
The macrophage scavenger receptor CD163.
Mature tissue macrophages form a first line of defense to recognize and eliminate potential pathogens; these specialized cells… (More)
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Highly Cited
2002
Highly Cited
2002
Identification of a novel family of oxidized phospholipids that serve as ligands for the macrophage scavenger receptor CD36.
The macrophage scavenger receptor CD36 plays an important role in the uptake of oxidized forms of low density lipoprotein (LDL… (More)
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Highly Cited
2000
Highly Cited
2000
Macrophage scavenger receptor CD36 is the major receptor for LDL modified by monocyte-generated reactive nitrogen species.
The oxidative conversion of LDL into an atherogenic form is considered a pivotal event in the development of cardiovascular… (More)
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Review
2000
Review
2000
Macrophage scavenger receptor class A: A multifunctional receptor in atherosclerosis.
In atherogenesis, elevated plasma levels of low density lipoprotein (LDL) lead to the chronic presence of LDL in the arterial… (More)
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Highly Cited
1996
Highly Cited
1996
Role for the class A macrophage scavenger receptor in the phagocytosis of apoptotic thymocytes in vitro.
Numerous immature thymocytes undergo apoptosis and are rapidly engulfed by phagocytic thymic macrophages. The macrophage surface… (More)
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Highly Cited
1994
Highly Cited
1994
The type I macrophage scavenger receptor binds to gram-positive bacteria and recognizes lipoteichoic acid.
Macrophage scavenger receptors exhibit unusually broad binding specificity for polyanionic ligands and have been implicated in… (More)
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Highly Cited
1990
Highly Cited
1990
Type I macrophage scavenger receptor contains α-helical and collagen-like coiled coils
The macrophage scavenger receptor is a trimeric membrane glycoprotein with unusual ligand-binding properties which has been… (More)
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Highly Cited
1990
Highly Cited
1990
Coiled-coil fibrous domains mediate ligand binding by macrophage scavenger receptor type II
THE macrophage scavenger receptor, which has been implicated in the pathogenesis of atherosclerosis1,2, has an unusually broad… (More)
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Highly Cited
1990
Highly Cited
1990
Type I macrophage scavenger receptor contains alpha-helical and collagen-like coiled coils.
The macrophage scavenger receptor is a trimeric membrane glycoprotein with unusual ligand-binding properties which has been… (More)
Is this relevant?