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MYLK wt Allele

Known as: Myosin, Light Polypeptide Kinase wt Allele, MLCK210, FLJ12216 
Human MYLK wild-type allele is located within 3q21 and is approximately 272 kb in length. This allele, which encodes myosin light chain kinase… 
National Institutes of Health

Related topics

Related topics

15 relations
3q21Calpain-2 Cell Motility PathwayFocal adhesion pathwayHomo sapiens

Broader (1)

MYLK gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Graft-versus-host disease propagation depends on increased intestinal epithelial tight junction permeability
Graft-versus-host disease (GVHD) is a complication of hematopoietic stem cell transplantation (HSCT) that affects multiple organs… 
2007
2007
MLCK210 gene knockout or kinase inhibition preserves lung function following endotoxin-induced lung injury in mice.
Barrier dysfunction, involving the endothelium or epithelium, is implicated in the pathophysiology of many disease states… 
Highly Cited
2007
Highly Cited
2007
Supervillin slows cell spreading by facilitating myosin II activation at the cell periphery
During cell migration, myosin II modulates adhesion, cell protrusion and actin organization at the leading edge. We show that an… 
Highly Cited
2005
Highly Cited
2005
Role of Rho, Rac, and Rho-kinase in phosphorylation of myosin light chain, development of polarity, and spontaneous migration of Walker 256 carcinosarcoma cells.
Highly Cited
2004
Highly Cited
2004
Distinct Roles of Different Neural Cell Adhesion Molecule (NCAM) Isoforms in Synaptic Maturation Revealed by Analysis of NCAM 180 kDa Isoform-Deficient Mice
Mice that lack all three major isoforms of neural cell adhesion molecule (NCAM) (180 and 140 kDa transmembrane, and 120 kDa… 
2003
2003
The catalytic domain of xPAK1 is sufficient to induce myosin II dependent in vivo cell fragmentation independently of other apoptotic events.
2002
2002
Constitutively active myosin light chain kinase alters axon guidance decisions in Drosophila embryos.
Conventional myosin II activity provides the motile force for axon outgrowth, but to achieve directional movement during axon… 
Review
1999
Review
1999
Pharmacomechanical coupling: the role of calcium, G-proteins, kinases and phosphatases.
The concept of pharmacomechanical coupling, introduced 30 years ago to account for physiological mechanisms that can regulate… 
Highly Cited
1986
Highly Cited
1986
The modulatory role of myosin light chain phosphorylation in human platelet activation.
Highly Cited
1960
Highly Cited
1960
Age and hormonal influences on aortic tissue metabolism
Summary1.Oxygen uptake of aortas of young rats is higher than that of old rats in KRP solution.2.In serum of young rats oxygen… 
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