MTHFD1 gene

Known as: MTHFD1, METHYLENETETRAHYDROFOLATE DEHYDROGENASE/METHENYLTETRAHYDROFOLATE CYCLOHYDROLASE/FORMYLTETRAHYDROFOLATE SYNTHETASE, NADP(+)-DEPENDENT, methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase 
This gene plays a role in folate metabolism.
National Institutes of Health

Topic mentions per year

Topic mentions per year

2002-2018
0102020022018

Papers overview

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2013
2013
Folate and vitamin B(12) metabolism are essential for de novo purine synthesis, and several defects in these pathways have been… (More)
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2012
2012
BACKGROUND MTHFD1 encodes C1-tetrahydrofolate synthase, which is a folate-dependent enzyme that catalyzes the formation and… (More)
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2011
2011
OBJECTIVE An infant was investigated because of megaloblastic anaemia, atypical hemolytic uraemic syndrome, severe combined… (More)
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2009
2009
Cytoplasmic folate-mediated one carbon (1C) metabolism functions to carry and activate single carbons for the de novo synthesis… (More)
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2009
2009
Methylenetetrahydrofolate dehydrogenase)methenyltetrahydrofolate cyclohydrolase)formyltetrahydrofolate synthetase (MTHFD1) is a… (More)
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2007
2007
Neurodegenerative diseases, such as Alzheimer's disease (AD) and Parkinson's disease (PD), are accompanied by increased levels of… (More)
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2005
2005
Low maternal folate or vitamin B12 status has been implicated in numerous pregnancy complications including spontaneous abortion… (More)
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Highly Cited
2004
Highly Cited
2004
ABSTRACTThe central role of 5,10-methylenetetrahydrofolate reductase (MTHFR) and methylenetetrahydrofolate dehydrogenase (MTHFD1… (More)
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Highly Cited
2002
Highly Cited
2002
Women who take folic acid periconceptionally reduce their risk of having a child with a neural tube defect (NTD) by >50%. A… (More)
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