Skip to search formSkip to main contentSkip to account menu

MTHFD1 gene

Known as: MTHFD1, METHYLENETETRAHYDROFOLATE DEHYDROGENASE/METHENYLTETRAHYDROFOLATE CYCLOHYDROLASE/FORMYLTETRAHYDROFOLATE SYNTHETASE, NADP(+)-DEPENDENT, methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase 
This gene plays a role in folate metabolism.
National Institutes of Health

Related topics

Related topics

8 relations
Bifunctional Methylenetetrahydrofolate Dehydrogenase/Cyclohydrolase, MitochondrialC-1-Tetrahydrofolate Synthase, CytoplasmicHydrolysisMTHFD1L gene

Narrower (1)

formyl-methenyl-methylenetetrahydrofolate synthetase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
MTHFR and MTHFD1 gene polymorphisms are not associated with pseudoexfoliation syndrome in South Indian population
PurposePseudoexfoliation syndrome (PEX) is a late onset disorder of extracellular matrix turnover, associated systemically with… 
2018
2018
Effects of MTHFD1 overexpression on lipid synthesis in the oleaginous fungus : Mortierella alpina
: Mortierella alpina is a filamentous fungus with a high polyunsaturated fatty acids content,but its sources of NADPH needed for… 
2017
2017
MTHFD1 and relevant biomarkers in cardiovascular disease: Observational studies in patients with suspected stable angina pectoris in Norway
2012
2012
Maternal Mthfd 1 disruption impairs fetal growth but does not cause neural tube defects in mice 1 – 3
Background: MTHFD1 encodes C1-tetrahydrofolate synthase, which is a folate-dependent enzyme that catalyzes the formation and… 
2012
2012
Distribution of MTHFD1 gene 1958G>A Polymorphism in the Jordanian Population and its Relation with Neural tube Defects
The frequency of methylenetetrahydrofolate dehydrogenase (MTHFD1) 1958G>A polymorphism was determined using restriction fragment… 
2011
2011
Folate-related Genes Polymorphisms Associated with the Risk of Childhood Leukaemia in the Malaysian Population
The folate and methionine metabolism play essential roles in DNA synthesis and DNA methylation, hence their metabolic pathways… 
2010
2010
Polimorfizm genów MTHFR, MTHFD1, MTR a stężenie homocysteiny i asymetrycznej dimetyloargininy oraz ich metabolitów u chorych z padaczką leczonych lekami przeciwpadaczkowymi
2009
2009
An association of the MTHFD1 c.1958G>A polymorphism in Polish women with epilepsy
2007
2007
Investigations of the human MTHFD1 promoter, folate response and neural tube defect risk
2006
2006
Polymorphism of MTHFR, MTR and MTHFD1 as related to the oxidative DNA damage, and the level of thiols in Alzheimer's and Parkinson’s diseases