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Bifunctional Methylenetetrahydrofolate Dehydrogenase/Cyclohydrolase, Mitochondrial
Known as:
MTHFD2
, NAD-Dependent Methylene Tetrahydrofolate Dehydrogenase Cyclohydrolase
Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial (350 aa, ~38 kDa) is encoded by the human MTHFD2 gene. This…
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National Institutes of Health
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Related topics
Related topics
7 relations
Enzyme Gene
Hydrolysis
MTHFD1 gene
Mitochondria
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
An investigation into the effect of p53, miRNA-22, and MTHFD2 in cancer metabolism
Tianlai Yang
2017
Corpus ID: 91377054
2016
2016
News and views
S. Houten
Journal of Inherited Metabolic Disease
2016
Corpus ID: 29244710
Recent work has established that the mechanistic target of rapamycin complex (mTORC) stimulates de novo purine (and pyrimidine…
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2016
2016
A serine-glycine metabolic enzyme MTHFD2 is a novel target for overcoming resistance in lung cancer
Gotoh Noriko
,
Nishimura Tatsunori
,
+4 authors
Tojo Arinobu
2016
Corpus ID: 116455967
2014
2014
Cancer Biology and Signal Transduction KRAS Mutation Status Is Associated with Enhanced Dependency on Folate Metabolism Pathways in Non – Small Cell Lung Cancer Cells
2014
Corpus ID: 46602810
KRAS genemutation is linked to poor prognosis and resistance to therapeutics in non–small cell lung cancer (NSCLC). In this study…
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