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MRC2 wt Allele

Known as: ENDO180, UPARAP, CD280 
Human MRC2 wild-type allele is located in the vicinity of 17q23.2 and is approximately 66 kb in length. This allele, which encodes C-type mannose… 
National Institutes of Health

Related topics

Related topics

4 relations
Extracellular Matrix DegradationLigand BindingReceptor Signaling

Broader (1)

MRC2 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2015
Review
2015
Mediated by a Lectin Domain Interaction of Endo 180 and CD 147
Epithelial cell–cell contacts maintain normal glandular tissue homeostasis, and their breakage can trigger epithelialto… 
Review
2014
Review
2014
Survival Outcome and EMT Suppression Mediated by a Lectin Domain Interaction of Endo180 and CD147
Epithelial cell–cell contacts maintain normal glandular tissue homeostasis, and their breakage can trigger epithelial-to… 
2014
2014
uPARAP Function in Cutaneous Wound Repair
Optimal skin wound healing relies on tight balance between collagen synthesis and degradation in new tissue formation and… 
2014
2014
Glyoxal leads to defective keratinocyte migration and down-regulation of Snai2.
2012
2012
TGFβ1–Endo180‐dependent collagen deposition is dysregulated at the tumour–stromal interface in bone metastasis
Cellular niches in adult tissue can harbour dysregulated microenvironments that become the driving force behind disease… 
2012
2012
Inhibitory Monoclonal Antibodies against Mouse Proteases Raised in Gene-Deficient Mice Block Proteolytic Functions in vivo
Identification of targets for cancer therapy requires the understanding of the in vivo roles of proteins, which can be derived… 
2008
2008
The Endocytic Collagen Receptor, uPARAP/Endo180, in Cancer Invasion and Tissue Remodeling
uPARAP/Endo180 is a constitutively recycling endocytosis receptor of 180 kDa. It is a type-1 membrane protein and includes an N… 
2008
2008
OC7. Inhibiting dickkopf-1 (Dkk-1) prevents the development of osteolytic bone disease in multiple myeloma
2005
2005
Endo180 Binds to the C-terminal Region of Type I Collagen*
Type I collagen is a fibril-forming heterotrimer composed of two α1 and one α2 chains and plays a crucial role in cell-matrix… 
2002
2002
Investigation of the role of Endo180/urokinase-type plasminogen activator receptor-associated protein as a collagenase 3 (matrix metalloproteinase 13) receptor.
Procollagenase 3 can be activated by interaction with and cleavage by the cell-associated membrane type 1 metalloproteinase (MT1… 
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