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MRC2 gene

Known as: endocytic receptor 180, UROKINASE-TYPE PLASMINOGEN ACTIVATOR RECEPTOR-ASSOCIATED PROTEIN, C-type lectin domain family 13 member E 
This gene is involved in extracellular matrix remodeling.
National Institutes of Health

Related topics

Related topics

5 relations
C-Type Mannose Receptor 2Extracellular Matrix DegradationLigand BindingReceptor Signaling

Narrower (1)

MRC2 wt Allele

Papers overview

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2015
2015
Frequent alterations in cytoskeleton remodelling genes in primary and metastatic lung adenocarcinomas
The landscape of genetic alterations in lung adenocarcinoma derived from Asian patients is largely uncharacterized. Here we… Expand
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2014
2014
Aptamer-based proteomic signature of intensive phase treatment response in pulmonary tuberculosis.
BACKGROUND New drug regimens of greater efficacy and shorter duration are needed for tuberculosis (TB) treatment. The… Expand
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2012
2012
Role of urokinase plasminogen activator receptor-associated protein in mouse lung.
Urokinase plasminogen activator receptor-associated protein (uPARAP, or Endo180) is a transmembrane endocytic receptor that… Expand
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2012
2012
TGFβ1-Endo180-dependent collagen deposition is dysregulated at the tumour-stromal interface in bone metastasis.
Cellular niches in adult tissue can harbour dysregulated microenvironments that become the driving force behind disease… Expand
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Highly Cited
2009
Highly Cited
2009
Balancing Selection of a Frame-Shift Mutation in the MRC2 Gene Accounts for the Outbreak of the Crooked Tail Syndrome in Belgian Blue Cattle
We herein describe the positional identification of a 2-bp deletion in the open reading frame of the MRC2 receptor causing the… Expand
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2009
2009
Membrane type-1 matrix metalloproteinase activity is regulated by the endocytic collagen receptor Endo180
The molecular interactions leading to organised, controlled extracellular matrix degradation are of central importance during… Expand
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2006
2006
Structural model for the mannose receptor family uncovered by electron microscopy of Endo180 and the mannose receptor.
The mannose receptor family comprises four members in mammals, Endo180 (CD280), DEC-205 (CD205), phospholipase A(2) receptor (PLA… Expand
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Highly Cited
2005
Highly Cited
2005
Gene expression profile of papillary thyroid cancer: sources of variability and diagnostic implications.
The study looked for an optimal set of genes differentiating between papillary thyroid cancer (PTC) and normal thyroid tissue and… Expand
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Highly Cited
2004
Highly Cited
2004
uPARAP/endo180 directs lysosomal delivery and degradation of collagen IV.
Collagen turnover is crucial for tissue homeostasis and remodeling and pathological processes such as cancer invasion, but the… Expand
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Highly Cited
2002
Highly Cited
2002
J-Shaped Relationship between Blood Pressure and Mortality in Hypertensive Patients: New Insights from a Meta-Analysis of Individual-Patient Data
Context Lowering blood pressure in hypertensive patients decreases the risk for cardiovascular events. However, clinical trials… Expand
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