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MRC2 gene

Known as: endocytic receptor 180, UROKINASE-TYPE PLASMINOGEN ACTIVATOR RECEPTOR-ASSOCIATED PROTEIN, C-type lectin domain family 13 member E 
This gene is involved in extracellular matrix remodeling.
National Institutes of Health

Papers overview

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2012
2012
Urokinase plasminogen activator receptor-associated protein (uPARAP, or Endo180) is a transmembrane endocytic receptor that… Expand
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Highly Cited
2010
Highly Cited
2010
Background Glioblastoma multiforme (GBM, WHO grade IV) is the most common and most malignant of astrocytic brain tumors, and is… Expand
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Highly Cited
2009
Highly Cited
2009
We herein describe the positional identification of a 2-bp deletion in the open reading frame of the MRC2 receptor causing the… Expand
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Highly Cited
2009
Highly Cited
2009
The molecular interactions leading to organised, controlled extracellular matrix degradation are of central importance during… Expand
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Highly Cited
2007
Highly Cited
2007
The collagens of the extracellular matrix are the most abundant structural proteins in the mammalian body. In tissue remodeling… Expand
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Highly Cited
2006
Highly Cited
2006
The mannose receptor family comprises four members in mammals, Endo180 (CD280), DEC-205 (CD205), phospholipase A2 receptor (PLA2R… Expand
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Highly Cited
2005
Highly Cited
2005
We recently reported that uPARAP/Endo180 can mediate the cellular uptake and lysosomal degradation of collagen by cultured… Expand
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Highly Cited
2005
Highly Cited
2005
The study looked for an optimal set of genes differentiating between papillary thyroid cancer (PTC) and normal thyroid tissue and… Expand
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Highly Cited
2004
Highly Cited
2004
Collagen turnover is crucial for tissue homeostasis and remodeling and pathological processes such as cancer invasion, but the… Expand
Highly Cited
2002
Highly Cited
2002
Context Lowering blood pressure in hypertensive patients decreases the risk for cardiovascular events. However, clinical trials… Expand