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MPTP Poisoning

Known as: MPTP Neurotoxicity Syndrome, MPTP-Induced Parkinsonism, Neurotoxicity Syndromes, MPTP 
A condition caused by the neurotoxin MPTP which causes selective destruction of nigrostriatal dopaminergic neurons. Clinical features include… 
National Institutes of Health

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1-Methyl-4-phenylpyridiniumIn BloodMicrobiologicalchemically induced

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2003
2003
Factores de riesgo en la enfermedad de Parkinson
Objetivo. Esta revision presenta y discute los principales factores de riesgo (FR) de la enfermedad de Parkinson (EP) aportados… 
2000
2000
Striatal enkephalin gene expression does not reflect parkinsonian sign
Loss of striatal dopamine has been associated with an increase in striatal enkephalin expression. However, the relationship… 
1994
1994
Deprenyl and the issue of neuroprotection.
Deprenyl and the Issue of Neuroprotection F. Vingerhoets, MD, Neurodegenerative Disorders Centre, University Hospital, UBC Site… 
1993
1993
Electroconvulsive shock does not modify striatal contents of dopamine in MPTP-treated mice
It has been suggested that the therapeutic response to electroconvulsive therapy in depressed patients could be mediated by… 
1992
1992
In vivo distribution of catecholamine reuptake sites in human brain gives clues to the physiopathology of MPTP-induced parkinsonism.
sarcoid meningitis with cranial nerve involvement.6 Transient benefit from chlorambucil in a case of sarcoid meningoencephalitis… 
1986
1986
Characterization of the neurotoxic potential of m-methoxy-MPTP and the use of its N-ethyl analogue as a means of avoiding exposure to a possible Parkinsonism-causing agent.
1-Methyl-4-(3-methoxyphenyl)-1,2,3,6-tetrahydropyridine (2) produced persistent depletion of striatal dopamine in mice after four… 
1986
1986
Persistent depletion of striatal dopamine in mice by m-hydroxy-MPTP.
: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) caused marked depletion of dopamine and of its two metabolites, DOPAC (3,4… 
1986
1986
Effect of increasing regimens of levodopa on chronic MPTP-induced parkinsonism in monkey; mechanographic and electromyographic data.
1986
1986
[New clues to the etiology of Parkinson disease: parkinsonism induced by the neurotoxin MPTP].
1984
1984
PET imaging of dopamine receptors in MPTP-induced parkinsonism
MPTP(N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) induces parkinsonism in animals and man by selectively destroying dopaminergic… 
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