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MMP1 protein, human

Known as: matrix metallopeptidase 1 (interstitial collagenase), human, MMP1, EC 3.4.24.7 
Interstitial collagenase (469 aa, ~54 kDa) is encoded by the human MMP1 gene. This protein plays a role in collagenolysis.
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Aims Matrix metalloproteinases (MMPs) play a major role in wound healing: they can degrade all components of the extracellular… Expand
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Highly Cited
2006
Highly Cited
2006
Pomegranate (Punica granatum) is an ancient fruit with exceptionally rich ethnomedical applications. The peel (pericarp) is well… Expand
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Highly Cited
2005
Highly Cited
2005
Background Idiopathic pulmonary fibrosis (IPF) is a progressive and lethal disorder characterized by fibroproliferation and… Expand
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Highly Cited
2005
Highly Cited
2005
Interleukin-1 (IL-1) plays a crucial role in the immunopathological responses involved with tissue destruction in chronic… Expand
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Highly Cited
2000
Highly Cited
2000
BACKGROUND Because hepatocyte growth factor (HGF) prevented and/or regressed fibrosis in liver and pulmonary injury models, HGF… Expand
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Highly Cited
1995
Highly Cited
1995
BACKGROUND In human atherosclerosis, most clinical events occur when plaque integrity is compromised and hemorrhage and… Expand
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Highly Cited
1992
Highly Cited
1992
The hydroxamic acid HONHCOCH2CH(i-Bu)CO-L-Trp-NHMe, isomer 6A (GM 6001), inhibits human skin fibroblast collagenase with Ki of 0… Expand
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Highly Cited
1990
Highly Cited
1990
Latent human fibroblast collagenase (HFC) can be activated by a variety of seemingly disparate means. In addition to the well… Expand
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Highly Cited
1986
Highly Cited
1986
We have determined the complete sequence of the cDNA clone representing the full size human skin collagenase mRNA. Collagenase is… Expand
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Highly Cited
1982
Highly Cited
1982
Summary Latent collagenase was activated by brief exposure to SDS and resolved by acrylamide slab gel electrophoresis in the… Expand
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