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Advanced nonsmall cell lung cancer (NSCLC) is associated with venous thromboembolism (VTE). However, to the authors' knowledge… Expand Background: BMS-275291 is a selective matrix metalloproteinase inhibitor (MMPI) that does not inhibit sheddases implicated in the… Expand PURPOSE
To determine whether BMS-275291, a broad-spectrum matrix metalloproteinase inhibitor (MMPI), added to systemic… Expand Purpose: This pilot trial was performed to evaluate the safety, pharmacokinetics and feasibility of incorporating BMS-275291, a… Expand Purpose: BMS-275291 is a novel broad-spectrum inhibitor of matrix metalloproteinase (MMPs) rationally designed to spare a class… Expand BACKGROUND
This randomized, double-blind, placebo-controlled study was designed to assess whether the addition of the matrix… Expand The MMPs2 are a family of zinc-containing endopeptidases that degrade various components of the ECM. A number of MMPs have been… Expand PURPOSE
The purpose of this study was to evaluate the feasibility of incorporating a novel wound angiogenesis assay into a Phase… Expand Bristol-Myers Squibb (BMS) is developing BMS-275291, which is a matrix metalloproteinase (MMP) inhibitor, for the potential… Expand BMS-275291 is an p.o. bioavailable, sulfhydryl-based matrix metalloproteinase (MMP) inhibitor currently in clinical development… Expand