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MMP14 protein, human

Known as: MMP-14, Membrane-Type-1 Matrix Metalloproteinase, membrane-type 1 matrix metalloproteinase, human 
Matrix metalloproteinase-14 (582 aa, ~66 kDa) is encoded by the human MMP14 gene. This protein is involved in both extracellular matrix proteolysis… 
National Institutes of Health

Related topics

Related topics

13 relations
BMS-275291Enzyme GeneHydrolysisInhibition of Matrix Metalloproteinases Pathway

Broader (1)

membrane-type 1 matrix metalloproteinase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Significance of semaphorin-3A and MMP-14 protein expression in non-small cell lung cancer
Semaphorin-3A is a chemorepellent guidance protein that is crucial in regulating the tumor microenvironment. MMP-14, a membrane… 
2009
2009
Epidermal Growth Factor Receptor–Mediated Membrane Type 1 Matrix Metalloproteinase Endocytosis Regulates the Transition between Invasive versus Expansive Growth of Ovarian Carcinoma Cells in Three…
The epidermal growth factor receptor (EGFR) is overexpressed in ovarian carcinomas and promotes cellular responses that… 
2006
2006
Expression of matrix metalloproteinase (MMP)‐2, MMP‐9, MMP‐13, and MT1‐MMP in skin tumors of human papillomavirus type 8 transgenic mice
Abstract:  Human papillomaviruses (HPV) are small DNA viruses that induce a wide variety of hyperproliferative lesions in… 
2005
2005
Competitive disruption of the tumor-promoting function of membrane type 1 matrix metalloproteinase/matrix metalloproteinase-14 in vivo
Membrane type 1 matrix metalloproteinase (MT1-MMP) is a potent modulator of the pericellular environment and promotes tumor cell… 
Highly Cited
2005
Highly Cited
2005
Transmigration of human ovarian adenocarcinoma cells through endothelial extracellular matrix involves αv integrins and the participation of MMP2
The growth of ovarian carcinoma is dependent upon their vascularistion, but the interaction of ovarian cancer cells with the… 
Highly Cited
2002
Highly Cited
2002
A Unique Substrate Binding Mode Discriminates Membrane Type-1 Matrix Metalloproteinase from Other Matrix Metalloproteinases*
In our study, we characterized the substrate recognition properties of membrane type-1 matrix metalloproteinase (MT1-MMP; also… 
Highly Cited
2000
Highly Cited
2000
Localization of MT1-MMP, TIMP-1, TIMP-2, and TIMP-3 messenger RNA in normal, hyperplastic, and neoplastic endometrium. Enhanced expression by endometrial adenocarcinomas is associated with low…
We studied membrane-type matrix metalloproteinase-1 (MT1-MMP), tissue inhibitor of metalloproteinase-1 (TIMP-1), TIMP-2, and TIMP… 
Highly Cited
1999
Highly Cited
1999
Gonadotropin-releasing hormone agonist has the ability to induce increased matrix metalloproteinase (MMP)-2 and membrane type 1-MMP expression in corpora lutea, and structural luteolysis in rats.
Gonadotropin-releasing hormone (GnRH) and its agonist analog (GnRHa) are well known to have luteolytic effects. We previously… 
1998
1998
Enhanced expression of membrane type-1 matrix metalloproteinase in mesangial proliferative glomerulonephritis.
Matrix metalloproteinase-2 (MMP-2, gelatinase A) is involved in the inflammatory and sclerotic events of glomerular diseases… 
1997
1997
Induction of membrane-type matrix metalloproteinase 1 (MT1-MMP) expression in human fibroblasts by breast adenocarcinoma cells
Membrane-type matrix metalloproteinase 1 (MT1-MMP) has been recently described as an activator of proMMP-2 (MMP-2) which is… 
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