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A placebo‐controlled trial of didanosine plus stavudine, with and without hydroxyurea, for HIV infection
Objective:To explore the short-term effects on surrogate markers for HIV progression of didanosine (ddI) plus stavudine (d4T), with or without hydroxyurea. Design:Randomized, double-blinded,… Expand
Decay of cell-associated HIV-1 DNA correlates with residual replication in patients treated during acute HIV-1 infection
ObjectivesTo evaluate the decay rate of cell-associated HIV-1 RNA and DNA and to identify factors associated with residual viral load in patients treated at the time of primary HIV-1 infection.… Expand
Detection of low HIV-1 RNA levels in plasma.
- G. A. Schockmel, S. Yerly, L. Perrin
- Biology, Medicine
- Journal of acquired immune deficiency syndromes…
- 1 February 1997
HIV-1 viremia is a marker of choice for staging, prognosis, and monitoring treatment efficiency in HIV infection. Among the commercial assays, the Amplicor HIV Monitor (Roche, Basel, Switzerland)… Expand
Hepatitis C virus in patients with cryoglobulinemia type II.
Transmission of antiretroviral-drug-resistant HIV-1 variants
BACKGROUND Resistance of HIV-1 to antiretroviral drugs is the main cause of antiretroviral-treatment failure. We assessed the transmission of drug-resistant variants among individuals with primary… Expand
Symptomatic primary infection due to human immunodeficiency virus type 1: review of 31 cases.
- S. Kinloch-de Löes, P. de Saussure, J. Saurat, H. Stalder, B. Hirschel, L. Perrin
- Clinical infectious diseases : an official…
- 1 July 1993
In this series of 31 patients with acute infection due to human immunodeficiency virus (HIV) type 1, the male-to-female ratio was 3.4:1 and the mean age was 31.3 years. Sexual transmission accounted… Expand
Epidemiological basis for clinical diagnosis of childhood malaria in endemic zone in West Africa
It is difficult to distinguish childhood malaria from other common febrile disorders by parasite count alone, because of the wide variation in tolerance of parasitaemia among individuals. We… Expand
Toxoplasma Encephalitis in Patients with the Acquired Immunodeficiency Syndrome
Among 504 cases of AIDS diagnosed between 1983 and 1990, there were 86 patients (17%) with toxoplasma encephalitis (TE). All were symptomatic at the time of diagnosis. General signs such as fever,… Expand
Nosocomial outbreak of multiple bloodborne viral infections.
In resource-limited countries, nosocomial transmission of bloodborne pathogens is a major public health concern. After a major outbreak of human immunodeficiency virus (HIV) infection in… Expand
Incubation time of acute human immunodeficiency virus (HIV) infection and duration of acute HIV infection are independent prognostic factors of progression to AIDS.
The severity and the duration of acute human immunodeficiency virus (HIV) infection (AHI) are associated with a faster rate of progression to AIDS, but the prognostic value of the length of… Expand