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MLL wt Allele

Known as: KMT2A wt Allele, MLL1, WDSTS 
Human KMT2A wild-type allele is located in the vicinity of 11q23 and is approximately 89 kb in length. This allele, which encodes histone-lysine N… 
National Institutes of Health

Related topics

Related topics

11 relations
B Acute Lymphoblastic Leukemia with t(v;11q23); MLL RearrangedB Lymphoblastic Leukemia/Lymphoma with t(v;11q23); MLL RearrangedHematopoiesisInfant Acute Lymphoblastic Leukemia with MLL Rearrangement

Broader (1)

KMT2A gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Cell context in the control of self-renewal and proliferation regulated by MLL1
Mixed lineage leukemia 1 (MLL1) is a gene that is disrupted by chromosomal translocation characteristically in a large proportion… 
2013
2013
Prospective study of cognitive function (cog fcn) in women with early-stage breast cancer (ESBC): Predictors of cognitive decline.
104 Background: Cog complaints are common among women receiving adjuvant therapy (Rx) for ESBC. Longitudinal prospective data is… 
Highly Cited
2011
Highly Cited
2011
HOXC6 Is transcriptionally regulated via coordination of MLL histone methylase and estrogen receptor in an estrogen environment.
2009
2009
Low frequency of MLL3 mutations in colorectal carcinoma.
2009
2009
DDB 1-CUL 4 and MLL 1 Mediate Oncogene-Induced p 16 INK 4 a Activation
The induction of cellular senescence by oncogenic signals acts as a barrier to cellular transformation and is attained, in part… 
2005
2005
Cryptic MLL-AF10 fusion caused by insertion of duplicated 5' part of MLL into 10p12 in acute leukemia: a case report.
2004
2004
Diabetes (db/db) mutation-induced female reproductive tract hypercytolipidemia: estrogenic restoration of utero-ovarian indices.
1997
1997
Multigenetic lesions in infant acute leukaemias: correlations with ALL‐1 gene status
In this study we investigated the presence of structural lesions in the ALL‐1, p53 and p16 (cyclin‐dependent kinase 4 inhibitor… 
1995
1995
Complex MLL rearrangement in a patient with T‐cell acute lymphoblastic leukemia
MLL (also known as ALL‐1, HTRX, or HRX) gene translocations are among the most common chromosomal abnormalities recognized in… 
1994
1994
Translocation t(11;11)(q13;q23) and HRX gene rearrangement associated with therapy-related leukemia in a child previously treated with VP16.
A child with acute myelomonocytic leukemia, bone marrow eosinophilia and inv(16) received first-line therapy including etoposide… 
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