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Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia.
TLDR
The revised criteria for behavioural variant frontotemporal dementia improve diagnostic accuracy compared with previously established criteria in a sample with known frontotmporal lobar degeneration and reflect the optimized diagnostic features, less restrictive exclusion features and a flexible structure that accommodates different initial clinical presentations.
Divergent network connectivity changes in behavioural variant frontotemporal dementia and Alzheimer's disease.
TLDR
The findings suggest that behavioural variant frontotemporal dementia and Alzheimer's disease lead to divergent network connectivity patterns, consistent with known reciprocal network interactions and the strength and deficit profiles of the two disorders.
Magnetic resonance imaging of the entorhinal cortex and hippocampus in mild cognitive impairment and Alzheimer's disease
TLDR
Using ERC and hippocampus together improved discrimination between AD and CN but did not improve discrimination between MCI and NC; the ERC was better than the hippocampus for distinguishing MCI from AD.
Patterns of brain atrophy in frontotemporal dementia and semantic dementia
TLDR
Although FTD and SemD are associated with different overall patterns of brain atrophy, regions of gray matter tissue loss in the orbital frontal, insular, and anterior cingulate regions are present in both groups and are suggested to underlie some the behavioral symptoms seen in the two disorders.
Diffusion tensor imaging of cingulum fibers in mild cognitive impairment and Alzheimer disease
TLDR
Assessment of the cingulum fibers using diffusion tensor imaging may aid early diagnosis of Alzheimer disease.
Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing
TLDR
A large genome-wide association meta-analysis of clinically diagnosed late-onset Alzheimer’s disease (LOAD) from 94,437 individuals identifies new LOAD risk loci and implicates Aβ formation, tau protein binding, immune response and lipid metabolism.
Different regional patterns of cortical thinning in Alzheimer's disease and frontotemporal dementia.
TLDR
Measurement of cortical thickness was similar to that of cortical volume in differentiating between normal ageing, Alzheimer's disease and FTD, suggesting that cortical thickness may be a useful surrogate marker for these types of dementia.
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