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KMT2A gene
Known as:
LYSINE-SPECIFIC METHYLTRANSFERASE 2A
, KMT2A
, CXXC FINGER PROTEIN 7
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This gene is involved in transcriptional regulation and alterations in the gene are associated with acute lymphoblastic leukemia.
National Institutes of Health
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Related topics
Related topics
20 relations
B Acute Lymphoblastic Leukemia with t(v;11q23); MLL Rearranged
B Lymphoblastic Leukemia/Lymphoma with t(v;11q23); MLL Rearranged
Hematopoiesis
Infant Acute Lymphoblastic Leukemia with MLL Rearrangement
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Narrower (1)
MLL wt Allele
Broader (1)
SEPT6 gene
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
t(9;11)(p21;q23) KMT2A/MLLT3
J. Knijnenburg
,
H. B. Beverloo
2018
Corpus ID: 90479509
Review
2016
Review
2016
Design , Synthesis and Characterization of Small Molecules Targeting MLL 1 Methyltransferase in Mixed-Lineage Leukemia
Ting‐Rong Chern
2016
Corpus ID: 3928912
The rearrangements of the MLL located on the chromosome 11q23 are the major cause of mixed-lineage leukemia. The translocation…
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2015
2015
Delineation of clinical features in Wiedemann – Steiner syndrome caused by KMT 2 A mutations
N. Okamotob
,
T. Koshoc
,
N. Brownd
,
T. Tane
,
P. J. J. Yape
2015
Corpus ID: 29676316
Wiedemann–Steiner syndrome (WSS) is an autosomal dominant congenital anomaly syndrome characterized by hairy elbows, dysmorphic…
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2015
2015
In vitro studies on the growth inhibitory effects of the lectin (MLL) purified from M. alba L. leaves
2015
Corpus ID: 55409145
2013
2013
[Establishment of the retrovirus-mediated murine model with MLL-AF9 leukemia].
Si-miao Xu
,
Yang Yang
,
+6 authors
Yong Fang
Zhongguo shi yan xue ye xue za zhi
2013
Corpus ID: 21447669
This study was purposed to establish a retrovirus-mediated murine model with MLL-AF9 leukemia, so as to provide a basis for…
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2005
2005
Inhibitory Effects of Mulberry Leaf Lectins to Silkworm Proteases
S. Ratanapo
,
Yuwadee Thawalvichit
,
A. Promboon
2005
Corpus ID: 59356019
Proteases from digestive fluid of Nang-lai strains of the Thai silkworm, Bombyx mori were partially purified by 40% ammonium…
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Review
2002
Review
2002
Analysis of Region 88 E 9 ; 88 F 2 in Drosophila melanogaster , Including the ear Gene Related to Human Factors Involved in Lineage-Specific Leukemias
Claudia B. Zraly
,
Yun Feng
,
A. Dingwall
2002
Corpus ID: 44036694
We identified and characterized the Drosophila gene ear (ENL/AF9-related), which is closely related to mammalian genes that have…
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Review
1998
Review
1998
2 ) in acute myeloid leukemia of infant twins fuses MLL with hCDC rel , a cell division cycle gene in the genomic region of deletion in DiGeorge and velocardiofacial syndromes
M. D. Megonigal
,
E. Rappaport
,
+7 authors
C. Felix
1998
Corpus ID: 27083086
We examined the MLL genomic translocation breakpoint in acute myeloid leukemia of infant twins. Southern blot analysis in both…
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1998
1998
Gène MLL (HRX, ALL-1, mixed-lineage leukemia)
T. Sousi
,
R. Berger
1998
Corpus ID: 78314995
1994
1994
Hunting 11q23 deletions with fluorescence in situ hybridization (FISH).
D. Cherif
,
O. Bernard
,
S. Paulien
,
M. James
,
D. Le Paslier
,
R. Berger
Leukemia
1994
Corpus ID: 20301661
Seven patients with acute leukemia and translocation involving band 11q23 have been studied by fluorescence in situ hybridization…
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